ARG80896
Human CA72-4 ELISA Kit
Human CA72-4 ELISA Kit for ELISA and Human
Cancer kit; Controls and Markers kit; Signaling Transduction kit
Overview
| Product Description | ARG80896 Human CA72-4 ELISA Kit is an enzyme immunoassay kit for the quantification of CA 72-4 (TAG-72) in serum and plasma (EDTA, heparin, citrate). |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | ELISA |
| Target Name | CA72-4 |
| Conjugation | HRP |
| Conjugation Note | Substrate: TMB and read at 450 nm |
| Sensitivity | 0.79 U/ml |
| Sample Type | Serum and plasma (EDTA, heparin, citrate). |
| Standard Range | 3 - 100 U/ml |
| Sample Volume | 20 µl |
Application Instructions
| Assay Time | 2 h, 30 min (RT) |
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Properties
| Form | 96 well |
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| Storage Instruction | Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Gene Full Name | Cancer antigen 72-4 |
|---|---|
| Background | CA 72-4 (Cancer antigen 72-4) was originally described as an antigenic determinant recognized by B 72.3, a murine monoclonal antibody raised against a membrane extract of mama carcinoma metastases. CA 72-4 was identified as a 1 MDa mucine-like Glycoprotein complex termed TAG-72 (tumor associated antigen 72). The molecular weight of the TAG-72 protein is 48 kD. Elevated CA 72-4 levels in serum and plasma have been reported in various malignant diseases including carcinomas of pancreas, stomach, gall, colon, mamma, ovaries, cervix and endometrium. The highest diagnostic sensitivities are found for carcinomas of the gastrointestinal tract and ovaries. Although some benign diseases such as rheumatic diseases or ovary cysts may also result in elevated levels of CA 72-4, clinical studies demonstrated diagnostic specificities of more than 95% for gastrointestinal and ovarian malignancies. There is a good correlation between CA 72-4 levels and tumor stage and size. CA 72-4 is the marker of choice for the therapeutic monitoring and follow-up care of gastrointestinal cancer patients. Suitable second markers are CA 19-9 or CEA. Additionally, CA 72-4 has been used as an independent marker for the therapeutic monitoring and follow-up care of ovarian cancer patients, in particular in CA 125 negative patients. |
| Highlight | Related products: New ELISA data calculation tool: Simplify the ELISA analysis by GainData |
| Research Area | Cancer kit; Controls and Markers kit; Signaling Transduction kit |
Images (1) Click the Picture to Zoom In
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ARG80896 Human CA72-4 ELISA Kit standard curve example image
The representative standard curve of ARG80896 Human CA72-4 ELISA Kit. The standard curve is for demonstration only and cannot be used in place of data generations at the time of assay. The standard curve should be generated each time the assay is performed.
| Title | Download Link |
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| ARG80896 Human CA72-4 ELISA Kit User's manual |
 Download
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