ARG83639
Human Apolipoprotein H ELISA Kit
Human Apolipoprotein H ELISA Kit for ELISA and Human
Overview
| Product Description | ARG83639 Human Apolipoprotein H ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human Apolipoprotein H in serum, plasma and urine |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | ELISA |
| Target Name | Apolipoprotein H |
| Conjugation | HRP |
| Conjugation Note | Substrate: TMB and read at 450 nm. |
| Sensitivity | 3.0 ng/ml |
| Sample Type | Serum, plasma and urine |
| Standard Range | 3.125 - 200 ng/ml |
| Sample Volume | 100 μl |
| Precision | Intra-Assay CV: < 10% Inter-Assay CV: < 10% |
| Alternate Names | APOH; Apolipoprotein H; B2G1; BG; Apolipoprotein H (Beta-2-Glycoprotein I); Activated Protein C-Binding Protein; Anticardiolipin Cofactor ; Beta-2-Glycoprotein I; Beta-2-Glycoprotein 1; APC Inhibitor; Beta(2)GPI; B2GPI; Apo-H; Epididymis Secretory Sperm Binding Protein; B2GP1 |
Application Instructions
| Assay Time | 2.5 hours |
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Properties
| Form | 96 well |
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| Storage Instruction | Store the kit at 4°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | APOH |
| Gene Full Name | Apolipoprotein H |
| Background | Apolipoprotein H, also known as beta-2-glycoprotein I, is a component of circulating plasma lipoproteins. It has been implicated in a variety of physiologic pathways including lipoprotein metabolism, coagulation, hemostasis, and the production of antiphospholipid autoantibodies. APOH may be a required cofactor for anionic phospholipid binding by the antiphospholipid autoantibodies found in sera of many patients with lupus and primary antiphospholipid syndrome (APS). The anti-beta (2) glycoprotein I antibodies from APS patients, mediate inhibition of activated protein C which has anticoagulant properties. Because beta-2-GPI is the main autoantigen in patients with APS, the disruption of this pathway by autoantibodies may be an important mechanism for thrombosis in patients with APS.[provided by RefSeq, Dec 2019] |
| Function | Binds to various kinds of negatively charged substances such as heparin, phospholipids, and dextran sulfate. May prevent activation of the intrinsic blood coagulation cascade by binding to phospholipids on the surface of damaged cells. [UniProt] |
| Title | Download Link |
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| Human Apolipoprotein H ELISA Kit User manual |
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