ARG81942
Human ACVRL1 ELISA Kit
Human ACVRL1 ELISA Kit for ELISA and Human
Component
| Cat No | Component Name | Package | Temp |
|---|---|---|---|
| ARG81942-001 | Antibody-coated microplate | 8 X 12 strips | 4°C. Unused strips should be sealed tightly in the air-tight pouch. |
| ARG81942-002 | Standard | 2 X 10 ng/vial | 4°C |
| ARG81942-003 | Standard/Sample diluent | 30 ml (Ready to use) | 4°C |
| ARG81942-004 | Antibody conjugate concentrate (100X) | 1 vial (100 µl) | 4°C |
| ARG81942-005 | Antibody diluent buffer | 12 ml (Ready to use) | 4°C |
| ARG81942-006 | HRP-Streptavidin concentrate (100X) | 1 vial (100 µl) | 4°C |
| ARG81942-007 | HRP-Streptavidin diluent buffer | 12 ml (Ready to use) | 4°C |
| ARG81942-008 | 25X Wash buffer | 20 ml | 4°C |
| ARG81942-009 | TMB substrate | 10 ml (Ready to use) | 4°C (Protect from light) |
| ARG81942-010 | STOP solution | 10 ml (Ready to use) | 4°C |
| ARG81942-011 | Plate sealer | 4 strips | Room temperature |
Overview
| Product Description | ARG81942 Human ACVRL1 ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human ACVRL1 in serum, plasma (heparin, EDTA) and cell culture supernatants. |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | ELISA |
| Specificity | There is no detectable cross-reactivity with other relevant proteins. |
| Target Name | ACVRL1 |
| Conjugation | HRP |
| Conjugation Note | Substrate: TMB and read at 450 nm. |
| Sensitivity | 23.45 pg/ml |
| Sample Type | Serum, plasma (heparin, EDTA) and cell culture supernatants. |
| Standard Range | 46.9 - 3000 pg/ml |
| Sample Volume | 100 µl |
| Precision | Intra-Assay CV: 5.1%; Inter-Assay CV: 5.6% |
| Alternate Names | ACVRLK1; ALK1; ORW2; ALK-1; HHT; EC 2.7.11.30; Serine/threonine-protein kinase receptor R3; TGF-B superfamily receptor type I; HHT2; SKR3; TSR-I; Activin receptor-like kinase 1 |
Application Instructions
| Assay Time | ~ 5 hours |
|---|
Properties
| Form | 96 well |
|---|---|
| Storage Instruction | Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # P37023 Human Serine/threonine-protein kinase receptor R3 |
|---|---|
| Gene Symbol | ACVRL1 |
| Gene Full Name | activin A receptor type II-like 1 |
| Background | This gene encodes a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. The encoded protein, sometimes termed ALK1, shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases. Mutations in this gene are associated with hemorrhagic telangiectasia type 2, also known as Rendu-Osler-Weber syndrome 2. [provided by RefSeq, Jul 2008] |
| Function | Type I receptor for TGF-beta family ligands BMP9/GDF2 and BMP10 and important regulator of normal blood vessel development. On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. May bind activin as well. [UniProt] |
| Highlight | Related products: ACVRL1 antibodies; ACVRL1 ELISA Kits; New ELISA data calculation tool: Simplify the ELISA analysis by GainData |
Images (1) Click the Picture to Zoom In
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ARG81942 Human ACVRL1 ELISA Kit standard curve image
ARG81942 Human ACVRL1 ELISA Kit results of a typical standard run with optical density reading at 450 nm.
| Title | Download Link |
|---|---|
| ARG81942 Human ACVRL1 ELISA Kit User manual |
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