ARG83347

Human ACE ELISA Kit

Human ACE ELISA Kit for ELISA and Human

Cancer kit; Cell Biology and Cellular Response kit; Developmental Biology kit; Metabolism kit; Signaling Transduction kit

Overview

Product Description ARG83347 Human ACE ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human ACE in serum, plasma, saliva and cell culture supernatants.
Tested Reactivity Hu
Tested Application ELISA
Specificity There is no detectable cross-reactivity with other relevant proteins.
Target Name ACE
Conjugation HRP
Conjugation Note Substrate: TMB and read at 450 nm.
Sensitivity 5 pg/ml
Detection Range 0.78 ng/ml - 50 ng/ml
Sample Type Serum, Plasma, Saliva and Cell culture supernatants.
Alternate Names DCP1; ICH; ACE; EC 3.2.1.-; MVCD3; Angiotensin-converting enzyme; Dipeptidyl carboxypeptidase I; CD143; CD antigen CD143; EC 3.4.15.1; Kininase II; ACE1; DCP

Application Instructions

Assay Time ~ 5 hours

Properties

Form 96 well
Storage Instruction Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 1636 Human ACE

Swiss-port # P12821 Human Angiotensin-converting enzyme

Gene Symbol ACE
Gene Full Name angiotensin I converting enzyme
Background This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Multiple alternatively spliced transcript variants encoding different isoforms have been identified, and two most abundant spliced variants encode the somatic form and the testicular form, respectively, that are equally active. [provided by RefSeq, May 2010]
Function Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilator. Has also a glycosidase activity which releases GPI-anchored proteins from the membrane by cleaving the mannose linkage in the GPI moiety. [UniProt]
Highlight Related products:
ACE antibodies; ACE ELISA Kits; ACE Duos / Panels; ACE recombinant proteins;
New ELISA data calculation tool:
Simplify the ELISA analysis by GainData
Research Area Cancer kit; Cell Biology and Cellular Response kit; Developmental Biology kit; Metabolism kit; Signaling Transduction kit
PTM Phosphorylated by CK2 on Ser-1299; which allows membrane retention.

Images (1) Click the Picture to Zoom In

  • ARG83347 Human ACE ELISA Kit standard curve image

    ARG83347 Human ACE ELISA Kit results of a typical standard run with optical density reading at 450 nm.

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