ARG80958
Human ACE ELISA Kit
Human ACE ELISA Kit for ELISA and Human
Cancer kit; Cell Biology and Cellular Response kit; Developmental Biology kit; Metabolism kit; Signaling Transduction kit
Overview
| Product Description | ARG80958 Human ACE ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human ACE in cell culture supernatant, cell lysates, serum, plasma and other suitable sample solution. |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | ELISA |
| Target Name | ACE |
| Conjugation | HRP |
| Sensitivity | 100 pg/ml |
| Sample Type | Cell culture supernatant, cell lysates, serum, plasma and other suitable sample solution. |
| Standard Range | 125 - 8000 pg/ml |
| Sample Volume | 100 µl |
| Alternate Names | DCP1; ICH; ACE; EC 3.2.1.-; MVCD3; Angiotensin-converting enzyme; Dipeptidyl carboxypeptidase I; CD143; CD antigen CD143; EC 3.4.15.1; Kininase II; ACE1; DCP |
Application Instructions
| Assay Time | 4 hours |
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Properties
| Form | 96 well |
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| Storage Instruction | Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | ACE |
| Gene Full Name | angiotensin I converting enzyme |
| Background | This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Multiple alternatively spliced transcript variants encoding different isoforms have been identified, and two most abundant spliced variants encode the somatic form and the testicular form, respectively, that are equally active. [provided by RefSeq, May 2010] |
| Function | Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilator. Has also a glycosidase activity which releases GPI-anchored proteins from the membrane by cleaving the mannose linkage in the GPI moiety. [UniProt] |
| Highlight | Related products: ACE antibodies; ACE ELISA Kits; ACE Duos / Panels; ACE recombinant proteins; New ELISA data calculation tool: Simplify the ELISA analysis by GainData |
| Research Area | Cancer kit; Cell Biology and Cellular Response kit; Developmental Biology kit; Metabolism kit; Signaling Transduction kit |
| PTM | Phosphorylated by CK2 on Ser-1299; which allows membrane retention. |
Images (1) Click the Picture to Zoom In
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ARG80958 Human ACE ELISA Kit standard curve image
ARG80958 Human ACE ELISA Kit results of a typical standard run with optical density reading at 450 nm.
| Title | Download Link |
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| ARG80958 Human ACE ELISA Kit User's manual |
 Download
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