ARG30341

Heterochromatin Foci Antibody Duo

Component

Cat No Component Name Host clonality Reactivity Application Package
ARG54763 anti-Histone H3 dimethyl (Lys9) antibody - ChIP-Grade Rabbit pAb Hu, Ms, Rat ICC/IF, IHC-P, WB, ChIP, ChIP-seq 50 μl
ARG53997 anti-CBX3 / HP1 gamma antibody Mouse mAb Hu, Ms, Rat, Hm, Mk ICC/IF, IHC-P, IP, WB 50 μl

Overview

Product Description Senescence-associated heterochromatin foci (SAHF) are specialized domains of facultative heterochromatin that play a role in sequestering proliferation-promoting genes. Detection of SAHF components is useful for identifying senescent cells.

This antibody duo comprises H3K9Me2 and HP1 gamma antibodies for labeling heterochromatin. It is the best solution to detect SAHF in human, mouse, and rat samples.

Properties

Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Images (7) Click the Picture to Zoom In

  • ARG53997 anti-CBX3 / HP1 gamma antibody ICC/IF image

    Immunofluorescence: HeLa cells fixed with 4% Paraformaldehyde and stained with ARG53997 anti-CBX3 / HP1 gamma antibody at 1:200 dilution.

  • ARG54763 anti-Histone H3 dimethyl (Lys9) antibody - ChIP-Grade ICC/IF image

    Immunofluorescence: 293T cells stained with ARG54763 anti-Histone H3 dimethyl (Lys9) antibody - ChIP-Grade.

  • ARG53997 anti-CBX3 / HP1 gamma antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded prostate cancer tissue stained with ARG53997 anti-CBX3 / HP1 gamma antibody at 1:200 dilution. Antigen Retrieval: Boil tissue section in Citrate buffer (pH 6.0).

  • ARG54763 anti-Histone H3 dimethyl (Lys9) antibody - ChIP-Grade IHC-P image

    Immunohistochemistry: Paraffin-embedded Mouse kidney tissue stained with ARG54763 anti-Histone H3 dimethyl (Lys9) antibody (ChIP-Grade) at 1:200 dilution.

  • ARG53997 anti-CBX3 / HP1 gamma antibody WB image

    Western blot: 3T3 cell lysate stained with ARG53997 anti-CBX3 / HP1 gamma antibody at 1:1000 dilution.

  • ARG54763 anti-Histone H3 dimethyl (Lys9) antibody - ChIP-Grade WB image

    Western blot: HeLa cell lysate and Recombinant Histone H3 protein expressed in E. coli (negative control) stained with ARG54763 anti-Histone H3 dimethyl (Lys9) antibody (ChIP-Grade).

  • ARG53997 anti-CBX3 / HP1 gamma antibody IP image

    Immunoprecipitation: HeLa cell lysates were immunoprecipitated and stained with ARG53997 anti-CBX3 / HP1 gamma antibody.