ARG83484
Hamster beta 2 Microglobulin ELISA Kit
Hamster beta 2 Microglobulin ELISA Kit for ELISA and Hamster
Overview
| Product Description | ARG83484 Hamster beta 2 Microglobulin ELISA Kit is an Enzyme Immunoassay kit for the quantification of Hamster beta 2 Microglobulin in Tissue culture media |
|---|---|
| Tested Reactivity | Hm |
| Tested Application | ELISA |
| Target Name | beta 2 Microglobulin |
| Conjugation | HRP |
| Conjugation Note | Substrate: TMB and read at 450 nm. |
| Sensitivity | 0.15 ng/mL |
| Sample Type | Tissue culture media |
| Standard Range | 0.3125 - 20 ng/mL |
| Sample Volume | 100 µl |
| Precision | Intra-Assay CV: < 10% Inter-Assay CV: < 10% |
| Alternate Names | B2M; Beta-2-Microglobulin; Beta Chain Of MHC Class I Molecules; Beta-2-Microglobin; IMD43 |
Application Instructions
| Assay Time | 3 hours |
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Properties
| Form | 96 well |
|---|---|
| Storage Instruction | Store the kit at 4°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Gene Symbol | B2M |
|---|---|
| Gene Full Name | beta-2-microglobulin |
| Background | This gene encodes a serum protein found in association with the major histocompatibility complex (MHC) class I heavy chain on the surface of nearly all nucleated cells. The protein has a predominantly beta-pleated sheet structure that can form amyloid fibrils in some pathological conditions. The encoded antimicrobial protein displays antibacterial activity in amniotic fluid. A mutation in this gene has been shown to result in hypercatabolic hypoproteinemia. |
| Function | Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. Exogenously applied M.tuberculosis EsxA or EsxA-EsxB (or EsxA expressed in host) binds B2M and decreases its export to the cell surface (total protein levels do not change), probably leading to defects in class I antigen presentation. |
| Cellular Localization | Amyloid, MHC I, Secreted |
| PTM | Disulfide bond, Glycation, Glycoprotein, Pyrrolidone carboxylic acid |
