ARG82812

Guinea Pig IL6 ELISA Kit

Guinea Pig IL6 ELISA Kit for ELISA and Guinea pig

Overview

Product Description ARG82812 Guinea Pig IL6 ELISA Kit is an Enzyme Immunoassay kit for the quantification of Guinea Pig IL6 in serum, plasma and cell culture supernatants.
Tested Reactivity Gpig
Tested Application ELISA
Specificity Cross-Reactivity: Not react with BMP2, BMP4, IL1 beta, IL2, IL4, IL5, IL8, IL10, IL15, IFN gamma, TGF beta 1, TLR1, TLR2, TLR3 and TNF alpha.
Target Name IL6
Conjugation HRP
Conjugation Note Substrate: TMB and read at 450 nm.
Sensitivity 23.5 pg/ml
Sample Type Serum, plasma and cell culture supernatants.
Standard Range 47 - 3000 pg/ml
Sample Volume 100 µl
Precision Intra-Assay CV: 7.0%
Inter-Assay CV: 8.0%
Alternate Names B-cell stimulatory factor 2; CDF; HSF; BSF-2; Interferon beta-2; IL-6; IFNB2; CTL differentiation factor; Interleukin-6; HGF; Hybridoma growth factor; BSF2; IFN-beta-2

Application Instructions

Assay Time ~ 3 hours

Properties

Form 96 well
Storage Instruction Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Gene Symbol IL6
Gene Full Name interleukin 6
Background This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in people with autoimmune diseases or infections. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
Function Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation. [UniProt]
Cellular Localization Secreted. [UniProt]
PTM N- and O-glycosylated. [UniProt]

Images (1) Click the Picture to Zoom In

  • ARG82812 Guinea Pig IL6 ELISA Kit standard curve image

    ARG82812 Guinea Pig IL6 ELISA Kit results of a typical standard run with optical density reading at 450 nm.

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