ARG82950

Goat IL4 ELISA kit

Goat IL4 ELISA kit for ELISA and Goat

Overview

Product Description ARG82950 Goat IL4 ELISA kit is an Enzyme Immunoassay kit for the quantification of Goat IL4 in serum, plasma and cell culture supernatants.
Tested Reactivity Goat
Tested Application ELISA
Target Name IL4
Conjugation HRP
Conjugation Note Substrate: TMB and read at 450 nm.
Protein Full Name Interleukin-4
Sensitivity 15.6 pg/ml
Sample Type Serum, plasma and cell culture supernatants.
Standard Range 31.25 - 2000 pg/ml
Sample Volume 100 μl
Precision Intra-Assay CV: < 10%
Inter-Assay CV: < 10%
Alternate Names BSF-1; IL4; B-cell stimulatory factor 1; BCGF1; Lymphocyte stimulatory factor 1; BCGF-1; Interleukin-4; Pitrakinra; Binetrakin; BSF1

Application Instructions

Assay Time ~ 3.5 hours

Properties

Form 96 well
Storage Instruction Store the kit at 4°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Gene Symbol IL4
Gene Full Name interleukin 4
Background The protein encoded by this gene is a pleiotropic cytokine produced by activated T cells. This cytokine is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. This gene, IL3, IL5, IL13, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL13. This gene, IL13 and IL5 are found to be regulated coordinately by several long-range regulatory elements in an over 120 kilobase range on the chromosome. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
Function Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. [UniProt]
Highlight Related products:
IL4 antibodies; IL4 ELISA Kits; IL4 recombinant proteins;
Related news:
HMGB1 in inflammation
Inflammatory Cytokines
New ELISA data calculation tool:
Simplify the ELISA analysis by GainData