ARG83491
Feline C Reactive Protein ELISA Kit
Feline C Reactive Protein ELISA Kit for ELISA and Cat
Overview
| Product Description | ARG83491 Feline C Reactive Protein ELISA Kit is an Enzyme Immunoassay kit for the quantification of Feline C Reactive Protein in Plasma and Serum |
|---|---|
| Tested Reactivity | Cat |
| Tested Application | ELISA |
| Target Name | C Reactive Protein |
| Conjugation | HRP |
| Conjugation Note | Substrate: TMB and read at 450 nm. |
| Sensitivity | 1.5 ng/ml |
| Sample Type | Plasma and Serum |
| Standard Range | 3.125 - 200 ng/ml |
| Sample Volume | 100 µl |
| Precision | Intra-Assay CV: less than 10% Inter-Assay CV: less than 10% |
| Alternate Names | CRP; C-Reactive Protein; PTX1; C-Reactive Protein, Pentraxin-Related; Pentraxin 1 |
Application Instructions
| Assay Time | 1.5 hour |
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Properties
| Form | 96 well |
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| Storage Instruction | Store the kit at 4°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Gene Symbol | CRP |
|---|---|
| Gene Full Name | C-reactive protein, pentraxin-related |
| Background | The protein encoded by this gene belongs to the pentraxin family which also includes serum amyloid P component protein and pentraxin 3. Pentraxins are involved in complement activation and amplification via communication with complement initiation pattern recognition molecules, but also complement regulation via recruitment of complement regulators. The encoded protein has a calcium dependent ligand binding domain with a distinctive flattened beta-jellyroll structure. It exists in two forms as either a pentamer in circulation or as a nonsoluble monomer in tissues. It is involved in several host defense related functions based on its ability to recognize foreign pathogens and damaged cells of the host and to initiate their elimination by interacting with humoral and cellular effector systems in the blood. Consequently, the level of this protein in plasma increases greatly during acute phase response to tissue injury, infection, or other inflammatory stimuli. Elevated expression of the encoded protein is associated with severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection. |
| Function | Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells. |
| Cellular Localization | Secreted |
| PTM | Disulfide bond, Pyrrolidone carboxylic acid |
| Title | Download Link |
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| ARG83491 Feline C Reactive Protein ELISA Kit User manual |
 Download
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