ARG82249
Diamine Oxidase Assay Kit (Fluorometric)
Diamine Oxidase Assay Kit (Fluorometric) for Functional study and All species
Overview
| Product Description | ARG82249 Diamine Oxidase Assay Kit (Fluorometric) can be used to measure Diamine Oxidase activity in serum and plasma. |
|---|---|
| Tested Reactivity | All |
| Tested Application | FuncSt |
| Target Name | Diamine Oxidase |
| Conjugation Note | λ ex/em = 530 / 585 nm (fluorometric) |
| Detection Range | 0.5 - 6 U/L |
| Sample Type | Serum and plasma. |
| Sample Volume | 10 µl |
| Alternate Names | Amine oxidase copper domain-containing protein 1; Amiloride-binding protein 1; Histaminase; KAO; DAO; ABP1; DAO1; Amiloride-sensitive amine oxidase [copper-containing]; ABP; Kidney amine oxidase; Diamine oxidase; EC 1.4.3.22 |
Application Instructions
| Application Note | Please note that this kit does not include a microplate. |
|---|---|
| Assay Time | 30 min |
Properties
| Form | Liquid |
|---|---|
| Storage Instruction | Store the kit at -20°C. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Gene Symbol | AOC1 |
|---|---|
| Gene Full Name | amine oxidase, copper containing 1 |
| Background | This gene encodes a metal-binding membrane glycoprotein that oxidatively deaminates putrescine, histamine, and related compounds. The encoded protein is inhibited by amiloride, a diuretic that acts by closing epithelial sodium ion channels. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2013] |
| Function | Catalyzes the degradation of compounds such as putrescine, histamine, spermine, and spermidine, substances involved in allergic and immune responses, cell proliferation, tissue differentiation, tumor formation, and possibly apoptosis. Placental DAO is thought to play a role in the regulation of the female reproductive function. [UniProt] |
| Cellular Localization | Secreted, extracellular space. [UniProt] |
| PTM | Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue. [UniProt] |
Images (1) Click the Picture to Zoom In
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ARG82249 Diamine Oxidase Assay Kit (Fluorometric) enzyme kinetics graph
Kinetics of 0.5 and 6 U/L Diamine Oxidase reaction, using ARG82249 Diamine Oxidase Assay Kit (Fluorometric).
| Title | Download Link |
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| ARG82249 Diamine Oxidase Assay Kit (Fluorometric) User manual |
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