ARG83180

Canine IL29 / IFN lambda ELISA Kit

Canine IL29 / IFN lambda ELISA Kit for ELISA and Dog

Immune System kit

Overview

Product Description ARG83180 Canine IL29 / IFN lambda ELISA Kit is an Enzyme Immunoassay kit for the quantification of Canine IL29 / IFN lambda in Serum, Plasma, Cell culture supernatants.
Tested Reactivity Dog
Tested Application ELISA
Specificity There is no detectable cross-reactivity with other relevant proteins.
Target Name IL29 / IFN lambda
Conjugation HRP
Conjugation Note Substrate: TMB and read at 450 nm.
Sensitivity 15 pg/ml
Detection Range 62.5 pg/ml - 4,000 pg/ml
Sample Type Serum, Plasma, Cell culture supernatants
Precision Intra-Assay CV: 4.7%
Inter-Assay CV: 6.9%
Alternate Names IFN-lambda-1; IL-29; Interferon lambda-1; Interleukin-29; Cytokine Zcyto21; IL29

Application Instructions

Assay Time ~ 5 hours

Properties

Form 96 well
Storage Instruction Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Gene Symbol IFNL1
Gene Full Name interferon, lambda 1
Background IL-29 is distantly related to type I interferons and the IL-10 family. Expression of IL-29 is induced by viral infection which interacts with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor beta (IL10RB) and interleukin 28 receptor alpha . IL-29 exhibits common features with type I IFNs such as antiviral activity, antiproliferative activity and in vivo antitumour activity. IL-29 acts similarly to IFNs, but is less effective generally and has activity in a more limited range of cell lines. IL-29 produced in response to viral infection, activates both monocytes and macrophages producing a restricted panel of cytokines and therefore is an important factor in activating innate immune responses at the site of viral infection. IFN-Lambda 1 antiviral and antiproliferative activity requires Interferon-Lambda 2 receptor tyrosine residues. Recombinant human IL-29 produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 181 amino acids and having a molecular mass of?20 kDa.
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Research Area Immune System kit

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  • ARG83180 Canine IL29 / IFN lambda ELISA Kit standard curve image

    ARG83180 Canine IL29 / IFN lambda ELISA Kit results of a typical standard run with optical density reading at 450 nm.

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