Monocyte chemotactic protein-1 (MCP-1) is also called monocyte chemotactic and activating factor (MCAF) and chemokine (C-C motif) ligand 2 (CCL2). It is primarily secreted by monocytes, macrophages and dendritic cells. This cytokine displayed chemotactic activity for monocytes, T-cells, and basophils, but not for neutrophils or eosinophils. MCAF causes the degranulation of basophils and mast cells, and augments the activity of monocyte and macrophage. MCAF plays an important role in inflammation, angiogenesis, auto-immune diseases, renal diseases, chronic infection and granuloma formation.

ARG30071 CCL2 / MCP1 ELISA Duos, includes a capture antibody, ARG10008 MCP1 / CCL-2 antibody [S14] and a HRP-conjugated tracer antibody, ARG10196 MCP1 antibody [S101] (HRP), for studying Monocyte chemotactic protein-1 (MCP-1) protein expression level by ELISA.