Search Result - Primary Antibodies

  • anti-CD3 epsilon (activation epitope) antibody [APA1/1]
  • Cat. No: ARG62807  (Mouse mAb)
  • Reactivity: Hu, Ms
  • Application: FACS, ICC/IF, IHC-Fr, IP, WB
  • Specificity: The clone APA1/1 recognizes an activation-dependent intracellular epitope of CD3 epsilon. Exposure of the epitope precedes CD3 phosphorylation and recruitment and activation of ZAP70, which initiates the signaling cascade produced by T-cell activation. APA1/1 provides the earliest known marker for TCR-mediated T cell activation.
  • Conjugation: Un-conjugated
  • anti-ZAP70 antibody [ZAP-03]
  • Cat. No: ARG65562  (Mouse mAb)
  • Reactivity: Hu
  • Application: FACS, ICC/IF, WB
  • Specificity: The clone ZAP-03 reacts with ZAP-70, a 70 kDa protein tyrosine kinase expressed in T and NK cells.
    ZAP-70 is a molecule susceptible to degradation. It is recommended to use freshly prepared cell lysates (protease inhibitors are essential) to avoid non-specific staining of degradation products.
  • Conjugation: Un-conjugated
  • anti-CD3 epsilon (activation epitope) antibody [APA1/1] (APC)
  • Cat. No: ARG42309  (Mouse mAb)
  • Reactivity: Hu, Ms
  • Application: FACS
  • Specificity: The mouse monoclonal antibody APA1/1 recognizes an activation-dependent intracellular epitope of CD3 epsilon. Exposure of the epitope precedes CD3 phosphorylation and recruitment and activation of ZAP70, which initiates the signaling cascade produced by T-cell activation. APA1/1 provides the earliest known marker for TCR-mediated T cell activation.
  • Conjugation: APC
  • anti-CD3 epsilon (activation epitope) antibody [APA1/1] (FITC)
  • Cat. No: ARG42316  (Mouse mAb)
  • Reactivity: Hu, Ms
  • Application: FACS
  • Specificity: The mouse monoclonal antibody APA1/1 recognizes an activation-dependent intracellular epitope of CD3 epsilon. Exposure of the epitope precedes CD3 phosphorylation and recruitment and activation of ZAP70, which initiates the signaling cascade produced by T-cell activation. APA1/1 provides the earliest known marker for TCR-mediated T cell activation.
  • Conjugation: FITC
  • anti-CD3 epsilon antibody [OKT3] (low endotoxin)
  • Cat. No: ARG62801  (Mouse mAb)
  • Reactivity: Hu
  • Application: FACS, IHC-Fr, FuncSt
  • Specificity: The clone OKT3 recognizes the CD3 antigen of the TCR/CD3 complex on mature human T cells. This antibody, also known as Orthoclone OKT3 or Muromonab-CD3, has been extensively used as a drug for therapy of acute, glucocorticoid resistant rejection of allogenic renal, heart and liver transplants. It has also been investigated for use in treating T-cell acute lymphoblastic leukemia.
    HLDA VI; WS Code T6T-R3
  • Conjugation: Un-conjugated
  • anti-CD3 epsilon antibody [OKT3]
  • Cat. No: ARG62804  (Mouse mAb)
  • Reactivity: Hu
  • Application: FACS, IHC-Fr, FuncSt
  • Specificity: The clone OKT3 recognizes the CD3 antigen of the TCR/CD3 complex on mature human T cells. This antibody, also known as Orthoclone OKT3 or Muromonab-CD3, has been extensively used as a drug for therapy of acute, glucocorticoid resistant rejection of allogenic renal, heart and liver transplants. It has also been investigated for use in treating T-cell acute lymphoblastic leukemia.
    HLDA VI; WS Code T6T-R3
  • Conjugation: Un-conjugated
  • anti-CD3 epsilon antibody [MEM-92] (low endotoxin)
  • Cat. No: ARG65502  (Mouse mAb)
  • Reactivity: Hu
  • Application: FACS, IP, FuncSt
  • Specificity: The clone MEM-92 reacts with epsilon chain of human CD3 complex, a part of a bigger multisubunit complex of the T cell receptor (CD3/TCR) expressed on peripheral blood T lymphocytes and mature thymocytes.
    HLDA IV.; WS Code T 97
  • Conjugation: Un-conjugated
  • anti-CD3 epsilon antibody [UCHT1] (PE)
  • Cat. No: ARG53820  (Mouse mAb)
  • Reactivity: Hu, NHuPrm
  • Application: FACS
  • Specificity: The clone UCHT1 recognizes the CD3 antigen of the TCR/CD3 complex on mature human T cells. The UCHT1 antibody reacts with the epsilon chain of the CD3 complex.
    HLDA I; WS Code T 3
    HLDA III; WS Code T 126
    HLDA III; WS Code T 471
    HLDA VI; WS Code T 6T-CD3.1
  • Conjugation: PE
  • anti-CD3 epsilon antibody [UCHT1] (PerCP)
  • Cat. No: ARG53822  (Mouse mAb)
  • Reactivity: Hu, NHuPrm
  • Application: FACS
  • Specificity: The clone UCHT1 recognizes the CD3 antigen of the TCR/CD3 complex on mature human T cells. The UCHT1 antibody reacts with the epsilon chain of the CD3 complex.
    HLDA I; WS Code T 3
    HLDA III; WS Code T 126
    HLDA III; WS Code T 471
    HLDA VI; WS Code T 6T-CD3.1
  • Conjugation: PerCP