ARG22614
anti-Integrin alpha 9 + beta 1 antibody [Y9A2]
anti-Integrin alpha 9 + beta 1 antibody [Y9A2] for CyTOF®-candidate,Flow cytometry,Functional study,Immunoprecipitation and Human,Guinea pig
Overview
| Product Description | Mouse Monoclonal antibody [Y9A2] recognizes Integrin alpha 9 + beta 1 This antibody recognizes human Integrin alpha 9/ beta 1, a receptor for VCAM1, cytotactin and osteopontin.In functional applications Mouse anti Human Integrin alpha 9 beta 1 antibody, clone Y9A2 has been shown to cause 100% inhibition of α9β1-mediated adhesion to the third fibronectin type III repeat in tenascin at <10ug/ml. Mouse anti Human Integrin alpha 9 beta 1 antibody, clone Y9A2 has been used to demonstrate Itgα9 blocking of progenitor cell proliferation (Schreiber et al. 2009). |
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| Tested Reactivity | Hu, Gpig |
| Tested Application | CyTOF®-candidate, FACS, FuncSt, IP |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | Y9A2 |
| Isotype | IgG1 |
| Target Name | Integrin alpha 9 + beta 1 |
| Antigen Species | Human |
| Immunogen | Murine L cells transfected with human alpha-9 integrin. |
| Conjugation | Un-conjugated |
| Alternate Names | Integrin alpha-9; ITGA4L; Integrin alpha-RLC; RLC; ALPHA-RLC |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
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| Purification | Purified |
| Buffer | PBS |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
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| Gene Symbol | ITGA9 |
| Gene Full Name | integrin, alpha 9 |
| Background | This gene encodes an alpha integrin. Integrins are heterodimeric integral membrane glycoproteins composed of an alpha chain and a beta chain that mediate cell-cell and cell-matrix adhesion. The protein encoded by this gene, when bound to the beta 1 chain, forms an integrin that is a receptor for VCAM1, cytotactin and osteopontin. Expression of this gene has been found to be upregulated in small cell lung cancers. [provided by RefSeq, Jul 2008] |
| Function | Integrin alpha-9/beta-1 (ITGA9:ITGB1) is a receptor for VCAM1, cytotactin and osteopontin. It recognizes the sequence A-E-I-D-G-I-E-L in cytotactin. [UniProt] |
| Highlight | Related products: Anti-Mouse IgG secondary antibodies; Related news: CyTOF-candidate Antibodies |
| Calculated MW | 114 kDa |
