New Dengue Virus NS1 antibodies and Antibody Duo

Dengue virus NS1 protein is a nonstructural protein which could be secreted and have been developed as diagnostic biomarker for early detection. There are several forms of NS1 including monomer, dimer, and hexamer. Dimeric NS1 can be anchored to cell membranes with glycosyl-phosphatidylinositol (GPI). Hexameric NS1 can be secreted and detected in patients’ blood samples (up to 50μg/mL) or infected cell supernatants (various from ng/mL to μg/mL depend on serotypes and strains). Studies have shown that NS1 proteins interfere with complement activity and prothrombin activation (1, 2). In addition, NS1 could elicit antibodies which cross-react with host antigens including coagulation factors and molecules expressed in endothelial cells and platelets through molecular mimic (3-5). References: 1.Avirutnan P, et al. J Exp Med. 2010 Apr 12;207(4):793-806. 2.Lin SW, et al. J Infect. 2012 Mar;64(3):325-34. 3.Falconar A K. Arch Virol. 1997;142(5):897-916. 4.Chuang YC, et al. Thromb Haemost. 2013 Aug;110(2):358-65. 5.Lin CF, et al. J Med Virol. 2003 Jan;69(1):82-90.
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
arigo has the best NS1 antibodies (ARG65660 anti-Dengue virus NS1 antibody [SQab1501]) in the market that recognize monomeric, dimeric and hexameric NS1 proteins by WB, ELISA, ICC/IF and FACS for DENV1/2/3/4.
ARG65660 anti-Dengue virus NS1 antibody [SQab1501]

ARG65660 anti-Dengue virus NS1 antibody [SQab1501] WB image		ARG65660 anti-Dengue virus NS1 antibody [SQab1501] ICC/IF image


ARG65660 anti-Dengue virus NS1 antibody [SQab1501] FACS image
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
ARG30252 Dengue virus NS1 ELISA Duo Dengue Virus NS1 Antibody Duo (ARG30252) offers the optimized antibody combination for Sandwich ELISA experiments.
		ARG65661 anti-Dengue virus NS1 antibody [SQab1502] & ARG65662 anti-Dengue virus NS1 antibody [SQab1503] (Biotin) ELISA image ELISA: E. coli expressed recombinant Dengue virus type 1-4 NS1 protein (major in monomer) detected by ARG65661 anti-Dengue virus NS1 antibody [SQab1502] as capture antibody (2.5 μg/ml), and ARG65662 anti-Dengue virus NS1 antibody [SQab1503] (Biotin) (0.5 μg/ml) as detection antibody, followed by incubation with streptavidin-HRP.

		ARG65661 anti-Dengue virus NS1 antibody [SQab1502] & ARG65662 anti-Dengue virus NS1 antibody [SQab1503] (Biotin) ELISA image ELISA: 293 cells expressed dengue virus type 2 NS1 protein (major in hexamer) detected by ARG65661 anti-Dengue virus NS1 antibody [SQab1502] as capture antibody (2.5 μg/ml), and ARG65662 anti-Dengue virus NS1 antibody [SQab1503] (Biotin) (0.5 μg/ml) as detection antibody, followed by incubation with streptavidin-HRP.
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

You might also like :
Dengue Virus IgG antibody ELISA Kit			Dengue Virus IgM antibody ELISA Kit
Cat. No: ARG80538 Application: ELISA Sensitivity: diagn. >90% Sample Type: Serum, Plasma			Cat. No: ARG80539 Application: ELISA Sensitivity: diagn. 90% Sample Type: Serum, Plasma