ARG83537

arigoQIKTM Human TNFRSF18 ELISA Development Kit

arigoQIKTM Human TNFRSF18 ELISA Development Kit for ELISA and Human

Overview

Product Description ARG83537 arigoQIKTM Human TNFRSF18 ELISA Development Kit, includes Capture antibody, Detection antibody, Standard, and HRP-Streptavidin Solution.
This ELISA Development Kit is designed for the development of sandwich ELISA to measure Human TNFRSF18 in serum, plasma and cell culture supernatants.

For other reagents required for arigoQIKTM ELISA Development Kit, please refer ARG83524 Integral Reagent Kit (ELISA Development Kit)

More about arigoQIKTM:
● Optimized capture and detection antibody pairs
● Reduced incubation time and wash cycles
● 2-hour quicker than conventional ELISA process
● 5- and 15-plate packages available
Tested Reactivity Hu
Tested Application ELISA
Target Name TNFRSF18
Conjugation HRP
Conjugation Note Substrate: TMB and read at 450 nm.
Sensitivity 15.63 pg/ml
Sample Type Serum, plasma and cell culture supernatants.
Standard Range 31.25 - 2000pg/ml
Sample Volume 50 μl
Precision Intra-Assay CV: < 10%
Inter-Assay CV: < 10%
Alternate Names TNFRSF18; TNF Receptor Superfamily Member 18; AITR; GITR; CD357; Tumor Necrosis Factor Receptor Superfamily Member 18; Glucocorticoid-Induced TNFR-Related Protein; Activation-Inducible TNFR Family Receptor; Tumor Necrosis Factor Receptor Superfamily, Member 18; TNF Receptor Superfamily Activation-Inducible Protein; CD357 Antigen; ENERGEN; GITR-D

Properties

Storage Instruction Store components at 4°C or -20°C. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 8784 Human TNFRSF18

Swiss-port # Q9Y5U5 Human Tumor necrosis factor receptor superfamily member 18

Gene Symbol TNFRSF18
Gene Full Name TNFRSF18
Background This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Feb 2011]
Function Receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated NF-kappa-B activation via the TRAF2/NIK pathway. [UniProt]
Cellular Localization Cell membrane, Membrane, Secreted. [UniProt]
PTM Disulfide bond, Glycoprotein. [UniProt]
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