ARG83584
arigoQIKTM Human CCL2 / MCP1 ELISA Development Kit
arigoQIKTM Human CCL2 / MCP1 ELISA Development Kit for ELISA and Human
Overview
| Product Description | ARG83584 arigoQIKTM Human CCL2 / MCP1 ELISA Development Kit, includes Capture antibody, Detection antibody, Standard, and HRP-Streptavidin Solution. This ELISA Development Kit is designed for the development of sandwich ELISA to measure Human CCL2 / MCP1 in Serum, plasma and cell culture supernatants. For other reagents required for arigoQIKTM ELISA Development Kit, please refer ARG83524 Integral Reagent Kit (ELISA Development Kit) More about arigoQIKTM: ● Optimized capture and detection antibody pairs ● Reduced incubation time and wash cycles ● 2-hour quicker than conventional ELISA process ● 5- and 15-plate packages available |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | ELISA |
| Target Name | CCL2 / MCP1 |
| Conjugation | HRP |
| Conjugation Note | Substrate: TMB and read at 450 nm. |
| Sensitivity | 7.8 pg/ml |
| Sample Type | Serum, plasma and cell culture supernatants. |
| Standard Range | 15.6 - 1000 pg/ml |
| Sample Volume | 50 μl |
| Precision | Intra-Assay CV: < 10% Inter-Assay CV: < 10% |
| Alternate Names | CCL2; C-C Motif Chemokine Ligand 2; MCP-1; MCP1; MCAF; HC11; Monocyte Chemotactic And Activating Factor; Monocyte Secretory Protein JE; SMC-CF 2; GDCF-2; SCYA2; Small Inducible Cytokine A2 (Monocyte Chemotactic Protein 1, Homologous To Mouse Sig-Je); Small Inducible Cytokine Subfamily A (Cys-Cys), Member 2; Monocyte Chemoattractant Protein-1; Chemokine (C-C Motif) Ligand 2; Monocyte Chemotactic Protein 1; Small-Inducible Cytokine A2; C-C Motif Chemokine 2; MGC9434; Monocyte Chemotactic Protein 1, Homologous To Mouse Sig-Je; Monocyte Chemoattractant Protein 1; HSMCR30 |
Properties
| Form | 96 well |
|---|---|
| Storage Instruction | Store components at 4°C or -20°C. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | CCL2 |
| Gene Full Name | C-C Motif Chemokine Ligand 2 |
| Background | This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Chemokines are a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of N-terminal cysteine residues of the mature peptide. This chemokine is a member of the CC subfamily which is characterized by two adjacent cysteine residues. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4. Elevated expression of the encoded protein is associated with severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection. [provided by RefSeq, Aug 2020] |
| Function | Exhibits a chemotactic activity for monocytes and basophils but not neutrophils or eosinophils. May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosi. [UniProt] |
| Cellular Localization | Secreted. [UniProt] |
| PTM | Disulfide bond, Glycoprotein, Pyrrolidone carboxylic acid. [UniProt] |
Images (1) Click the Picture to Zoom In
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ARG83584 arigoQIK Human CCL2 / MCP1 ELISA Development Kit standard curve image
ARG83584 arigoQIK Human CCL2 / MCP1 ELISA Development Kit results of a typical standard run with optical density reading at 450 nm.
| Title | Download Link |
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| ARG83584 arigoQIKTM Human CCL2 / MCP1 ELISA Development Kit User manual |
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