ARG11152
anti-Visinin like 1 antibody [3A9]
anti-Visinin like 1 antibody [3A9] for IHC-Frozen sections,Western blot and Human,Mouse,Rat,Cow,Pig
Overview
| Product Description | Mouse Monoclonal antibody [3A9] recognizes Visinin like 1 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat, Cow, Pig |
| Tested Application | IHC-Fr, WB |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | 3A9 |
| Isotype | IgG1 |
| Target Name | Visinin like 1 |
| Antigen Species | Human |
| Immunogen | Recombinant full-length Human Visinin like 1. |
| Conjugation | Un-conjugated |
| Alternate Names | HPCAL3; HUVISL1; Visinin-like protein 1; HLP3; Hippocalcin-like protein 3; VILIP; VLP-1; VILIP-1 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| Observed Size | ~ 18 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Purified |
| Buffer | PBS, 5 mM Sodium azide and 50% Glycerol. |
| Preservative | 5 mM Sodium azide |
| Stabilizer | 50% Glycerol |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | VSNL1 |
| Gene Full Name | visinin-like 1 |
| Background | This gene is a member of the visinin/recoverin subfamily of neuronal calcium sensor proteins. The encoded protein is strongly expressed in granule cells of the cerebellum where it associates with membranes in a calcium-dependent manner and modulates intracellular signaling pathways of the central nervous system by directly or indirectly regulating the activity of adenylyl cyclase. Alternatively spliced transcript variants have been observed, but their full-length nature has not been determined. [provided by RefSeq, Jul 2008] |
| Function | Regulates (in vitro) the inhibition of rhodopsin phosphorylation in a calcium-dependent manner. [UniProt] |
| Calculated MW | 22 kDa |
Images (2) Click the Picture to Zoom In
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ARG11152 anti-Visinin like 1 antibody [3A9] IHC-Fr image
Immunohistochemistry: Frozen section of adult rat cerebellum tissue stained with ARG11152 anti-Visinin like 1 antibody [3A9] (green) at 1:1000 dilution, and co-stained with anti-MAP2 antibody (red) at 1:10000 dilution. DAPI (blue) for nuclear staining.
Visinin like 1 antibody reveals perikarya and synaptic regions in the neuron rich granular layer (bottom) and synapse rich molecular layer (top). Note that the large prominent Purkinje neurons at the junction of these two layers do not stain with the Visinin like 1 antibody.
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ARG11152 anti-Visinin like 1 antibody [3A9] WB image
Western blot: Rat brain, Mouse brain, Pig hippocampus and Cow cerebellum lysates stained with ARG11152 anti-Visinin like 1 antibody [3A9] at 1:1000 dilution.
