ARG52461
anti-Tyrosine Hydroxylase antibody
anti-Tyrosine Hydroxylase antibody for ICC/IF,IHC-Frozen sections,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat,Mammal
Cancer antibody; Metabolism antibody; Neuroscience antibody
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Overview
Product Description | Rabbit Polyclonal antibody recognizes Tyrosine Hydroxylase |
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Tested Reactivity | Hu, Ms, Rat, Mamm |
Tested Application | ICC/IF, IHC-Fr, IHC-P, WB |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | IgG |
Target Name | Tyrosine Hydroxylase |
Antigen Species | Rat |
Immunogen | SDS-denatured rat tyrosine hydroxylase purified from pheochromocytoma |
Conjugation | Un-conjugated |
Alternate Names | DYT14; TYH; Tyrosine 3-monooxygenase; Tyrosine 3-hydroxylase; TH; DYT5b; EC 1.14.16.2 |
Application Instructions
Application Suggestion |
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Application Note | Specific for the ~60k tyrosine hydroxylase protein. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
Form | Liquid |
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Purification | Affinity Purified |
Buffer | 10 mM HEPES (pH 7.5), 150 mM NaCl, 0.1 mg/ml BSA and 50% Glycerol |
Stabilizer | 0.1 mg/ml BSA, 50% Glycerol |
Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
Database Links | |
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Gene Symbol | TH |
Gene Full Name | tyrosine hydroxylase |
Background | Tyrosine hydroxylase (TH) is the rate-limiting enzyme in the synthesis of the catecholamines dopamine and norepinephrine. TH antibodies can therefore be used as markers for dopaminergic and noradrenergic neurons in a variety of applications including depression, schizophrenia, Parkinson’s disease and drug abuse (Kish et al., 2001; Zhu et al., 2000; Zhu et al., 1999). TH antibodies can also be used to explore basic mechanisms of dopamine and norepinephrine signaling (Witkovsky et al., 2000; Salvatore et al., 2001; Dunkley et al., 2004). |
Highlight | Related Antibody Duos and Panels: ARG30212 Phospho Tyrosine Hydroxylase Antibody Panel (Total, pS31, pS40) Related products: Tyrosine Hydroxylase antibodies; Tyrosine Hydroxylase Duos / Panels; Anti-Rabbit IgG secondary antibodies; Related news: Astrocyte-to-neuron conversion for Parkinson's disease treatment |
Research Area | Cancer antibody; Metabolism antibody; Neuroscience antibody |
Calculated MW | 59 kDa |
Images (4) Click the Picture to Zoom In
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ARG52461 anti-Tyrosine Hydroxylase antibody WB image
Western blot: 30 µg of Mouse brain tissue lysate stained with ARG52461 anti-Tyrosine Hydroxylase antibody at 1:500 dilution.
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ARG52461 anti-Tyrosine Hydroxylase antibody IHC-Fr image
Immunohistochemistry: Frozen section of Mouse brain stained with ARG52461 anti-Tyrosine Hydroxylase antibody at 1:1000 dilution.
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ARG52461 anti-TH antibody WB image
Western Blot: 10 μg of rat caudate lysate showing specific immunolabeling of the ~60k TH protein stained with TH antibody (ARG52461).
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