ARG53989
anti-TBL1X antibody
anti-TBL1X antibody for ICC/IF,Western blot and Human
Cancer antibody; Gene Regulation antibody; Metabolism antibody; Neuroscience antibody
Overview
| Product Description | Mouse Monoclonal antibody recognizes TBL1X |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | ICC/IF, WB |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG2b |
| Target Name | TBL1X |
| Antigen Species | Human |
| Immunogen | Purified recombinant human TBL1 protein fragments expressed in E.coli. |
| Conjugation | Un-conjugated |
| Alternate Names | Transducin beta-like protein 1X; Transducin-beta-like protein 1, X-linked; EBI; SMAP55; TBL1; F-box-like/WD repeat-containing protein TBL1X |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| Observed Size | 58 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified |
| Buffer | PBS (pH 7.4), 0.02% Sodium azide and 50% Glycerol |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # O60907 Human F-box-like/WD repeat-containing protein TBL1X |
|---|---|
| Gene Symbol | TBL1X |
| Gene Full Name | transducin (beta)-like 1X-linked |
| Background | F-box-like protein involved in the recruitment of the ubiquitin/19S proteasome complex to nuclear receptor-regulated transcription units. Plays an essential role in transcription activation mediated by nuclear receptors. Probably acts as integral component of corepressor complexes that mediates the recruitment of the 19S proteasome complex, leading to the subsequent proteasomal degradation of transcription repressor complexes, thereby allowing cofactor exchange. |
| Function | F-box-like protein involved in the recruitment of the ubiquitin/19S proteasome complex to nuclear receptor-regulated transcription units. Plays an essential role in transcription activation mediated by nuclear receptors. Probably acts as integral component of corepressor complexes that mediates the recruitment of the 19S proteasome complex, leading to the subsequent proteasomal degradation of transcription repressor complexes, thereby allowing cofactor exchange. [UniProt] |
| Cellular Localization | Nucleus |
| Research Area | Cancer antibody; Gene Regulation antibody; Metabolism antibody; Neuroscience antibody |
| Calculated MW | 62 kDa |
Images (2) Click the Picture to Zoom In
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ARG53989 anti-TBL1X antibody ICC/IF image
Immunofluorescence: HeLa cells fixed with 4% Paraformaldehyde and stained with ARG53989 anti-TBL1X antibody at 1:100 dilution.
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ARG53989 anti-TBL1X antibody WB image
Western blot: SW480 cell lysate stained with ARG53989 anti-TBL1X antibody at 1:1000 dilution.
