ARG57814
anti-SOAT2 / ACAT2 antibody
anti-SOAT2 / ACAT2 antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat,Pig,Sheep
Publication1
Overview
| Product Description | Rabbit Polyclonal antibody recognizes SOAT2 / ACAT2 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat, Pig, Sheep |
| Tested Application | ICC/IF, IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | SOAT2 / ACAT2 |
| Antigen Species | Human |
| Immunogen | Synthetic peptide around the N-terminus of Human SOAT2 / ACAT2. |
| Conjugation | Un-conjugated |
| Alternate Names | Cholesterol acyltransferase 2; ACACT2; ACAT-2; Sterol O-acyltransferase 2; ACAT2; ARGP2; Acyl-coenzyme A:cholesterol acyltransferase 2; EC 2.3.1.26 |
Application Instructions
| Application Suggestion |
|
||||||||
|---|---|---|---|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | TBS (pH 7.4), 0.02% Sodium azide, 50% Glycerol and 0.1% BSA. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol and 0.1% BSA |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | SOAT2 |
| Gene Full Name | sterol O-acyltransferase 2 |
| Background | Summary:This gene is a member of a small family of acyl coenzyme A:cholesterol acyltransferases. The gene encodes a membrane-bound enzyme localized in the endoplasmic reticulum that produces intracellular cholesterol esters from long-chain fatty acyl CoA and cholesterol. The cholesterol esters are then stored as cytoplasmic lipid droplets inside the cell. The enzyme is implicated in cholesterol absorption in the intestine and in the assembly and secretion of apolipoprotein B-containing lipoproteins such as very low density lipoprotein (VLDL). Several alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Jul 2008] |
| Function | Plays a role in lipoprotein assembly and dietary cholesterol absorption. In addition to its acyltransferase activity, it may act as a ligase. May provide cholesteryl esters for lipoprotein secretion from hepatocytes and intestinal mucosa. [UniProt] |
| Highlight | Related products: Anti-Rabbit IgG secondary antibodies; Related news: Cholesterol, the weakness of anaplastic large cell lymphoma (ALCL) |
| Calculated MW | 60 kDa |
Images (1) Click the Picture to Zoom In
-
ARG57814 anti-SOAT2 / ACAT2 antibody WB image
Western blot: 30 µg of Mouse liver, 30 µg of JGC-1, 30 µg of Jurkat and 60 µg of Rat liver lysates stained with ARG57814 anti-SOAT2 / ACAT2 antibody.
Specific References
Sterol O-acyltransferase 2 chaperoned by apolipoprotein J facilitates hepatic lipid accumulation following viral and nutrient stresses.
WB / Human
