ARG44524
anti-SLC25A25 / APC3 antibody
anti-SLC25A25 / APC3 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot,Flow cytometry and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes SLC25A25 / APC3 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | FACS, IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Target Name | SLC25A25 / APC3 |
| Antigen Species | Human |
| Immunogen | Human SLC25A25 / APC3 recombinant protein |
| Conjugation | Un-conjugated |
| Alternate Names | SLC25A25; Solute Carrier Family 25 Member 25 ; KIAA1896; PCSCL; MCSC; Solute Carrier Family 25 (Mitochondrial Carrier; Phosphate Carrier), Member 25; Mitochondrial Ca(2+)-Dependent Solute Carrier Protein 3; Short Calcium-Binding Mitochondrial Carrier Protein 2; Mitochondrial Adenyl Nucleotide Antiporter SLC25A25; Mitochondrial ATP-Mg/Pi Carrier Protein 3; SCAMC2; Calcium-Binding Mitochondrial Carrier Protein SCaMC-2; Short Calcium-Binding Mitochondrial Carrier 2; Small Calcium-Binding Mitochondrial Carrier 2; SCAMC-2; SCaMC-2; MCSC3; APC3 |
Application Instructions
| Application Suggestion |
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| Application Note | The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 4% Trehalose. |
| Preservative | 0.05% Sodium azide |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | SLC25A25 |
| Gene Full Name | Solute Carrier Family 25 Member 25 |
| Background | The protein encoded by this gene belongs to the family of calcium-binding mitochondrial carriers, with a characteristic mitochondrial carrier domain at the C-terminus. These proteins are found in the inner membranes of mitochondria, and function as transport proteins. They shuttle metabolites, nucleotides and cofactors through the mitochondrial membrane and thereby connect and/or regulate cytoplasm and matrix functions. This protein may function as an ATP-Mg/Pi carrier that mediates the transport of Mg-ATP in exchange for phosphate, and likely responsible for the net uptake or efflux of adenine nucleotides into or from the mitochondria. Alternatively spliced transcript variants encoding different isoforms with a common C-terminus but variable N-termini have been described for this gene. |
| Function | Electroneutral antiporter that most probably mediates the transport of adenyl nucleotides through the inner mitochondrial membrane. Originally identified as an ATP-magnesium/inorganic phosphate antiporter, it could have a broader specificity for adenyl nucleotides. By regulating the mitochondrial matrix adenyl nucleotide pool could adapt to changing cellular energetic demands and indirectly regulate adenyl nucleotide-dependent metabolic pathways. |
| Cellular Localization | Membrane, Mitochondrion, Mitochondrion inner membrane |
| Calculated MW | 53 kDa |
Images (5) Click the Picture to Zoom In
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ARG44524 anti-SLC25A25 / APC3 antibody IHC-P image
Immunohistochemistry: Human prostate cancer stained with ARG44524 anti-SLC25A25 / APC3 antibody at 2 μg/mL dilution.
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ARG44524 anti-SLC25A25 / APC3 antibody WB image
Western blot: K562, SiHa, Jurkat and MCF-7 stained with ARG44524 anti-SLC25A25 / APC3 antibody at 0.5 μg/mL dilution.
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ARG44524 anti-SLC25A25 / APC3 antibody FACS image
Flow Cytometry: JK stained with ARG44524 anti-SLC25A25 / APC3 antibody at 1 μg/10^6 cells dilution.
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ARG44524 anti-SLC25A25 / APC3 antibody WB image
Western blot: Rat liver stained with ARG44524 anti-SLC25A25 / APC3 antibody at 0.5 μg/mL dilution.
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ARG44524 anti-SLC25A25 / APC3 antibody WB image
Western blot: RAW264.7 stained with ARG44524 anti-SLC25A25 / APC3 antibody at 0.5 μg/mL dilution.
