ARG44910
anti-RECQL antibody
anti-RECQL antibody for IHC-Formalin-fixed paraffin-embedded sections and Human
Overview
| Product Description | Mouse Monoclonal antibody recognizes RECQL |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | IHC-P |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG1 |
| Target Name | RECQL |
| Antigen Species | Human |
| Epitope | LDSITSELHA VEIQIQELTE RQQELIQKKK VLTKKIKQCL EDSDAGASNE YDSSPAAWNK EDFPWSGKVK DILQNVFKLE |
| Conjugation | Un-conjugated |
| Alternate Names | RECQL; RecQ Like Helicase; RecQ1; RecQL1; RecQ Protein-Like (DNA Helicase Q1-Like); DNA Helicase, RecQ-Like Type 1; ATP-Dependent DNA Helicase Q1; DNA-Dependent ATPase Q1; DNA 3'-5' Helicase Q1; RecQ Protein-Like 1; RecQ Helicase-Like; DNA Helicase Q1-Like; EC 5.6.2.4; EC 3.6.1; RECQL1; RECON; RECQ1 |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Protein A purification |
| Buffer | PBS with 0.09% sodium azide |
| Preservative | 0.09% sodium azide |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Gene Symbol | RECQL |
|---|---|
| Gene Full Name | RecQ Like Helicase |
| Background | The protein encoded by this gene is a member of the RecQ DNA helicase family. DNA helicases are enzymes involved in various types of DNA repair, including mismatch repair, nucleotide excision repair and direct repair. The encoded protein is involved in the processing of Holliday junctions, the suppression of sister chromatid exchanges, telomere maintenance, and is required for genotoxic stress resistance. Defects in this gene have been associated with several types of cancer. [provided by RefSeq, Jan 2017] |
| Function | May play a role in the repair of DNA that is damaged by ultraviolet light or other mutagens. [Uniprot] |
| Cellular Localization | Nucleus. [Uniprot] |
| Calculated MW | 73 kDa |
| PTM | Acetylation, Phosphoprotein. [Uniprot] |
Images (2) Click the Picture to Zoom In
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ARG44910 anti-RECQL antibody IHC-P image
Immunohistochemistry: Human heart muscle stained with ARG44910 anti-RECQL antibody at 5.57 µg/mL dilution.
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ARG44910 anti-RECQL antibody IP image
Immunoprecipitation: HeLa lysate immunoprecipitated with 2.5 µg of ARG44910 anti-RECQL antibody.
