ARG55653

anti-REA antibody

anti-REA antibody for IHC-Formalin-fixed paraffin-embedded sections,Immunoprecipitation,Western blot and Human,Mouse,Rat

Overview

Product Description Rabbit Polyclonal antibody recognizes REA
Tested Reactivity Hu, Ms, Rat
Tested Application IHC-P, IP, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name REA
Antigen Species Human
Immunogen Recombinant protein of Human REA
Conjugation Un-conjugated
Alternate Names BAP; Bap37; BCAP37; D-prohibitin; Repressor of estrogen receptor activity; Prohibitin-2; PNAS-141; B-cell receptor-associated protein BAP37; p22; hBAP; REA

Application Instructions

Application Suggestion
Tested Application Dilution
IHC-P1:50-1:200
IP1:20-1:50
WB1:500-1:2000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control A549
Observed Size 33 kDa

Properties

Form Liquid
Purification Affinity purification with immunogen.
Buffer PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol.
Preservative 0.02% Sodium azide
Stabilizer 50% Glycerol
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 11331 Human PHB2

GeneID: 114766 Rat PHB2

GeneID: 12034 Mouse PHB2

Gene Symbol PHB2
Gene Full Name prohibitin 2
Function Acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases (By similarity). Functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. Competes with NCOA1 for modulation of ER transcriptional activity. Probably involved in regulating mitochondrial respiration activity and in aging. [UniProt]
Calculated MW 33 kDa

Images (2) Click the Picture to Zoom In

  • ARG55653 anti-REA antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Human esophagus stained with ARG55653 anti-REA antibody.

  • ARG55653 anti-REA antibody WB image

    Western blot: A549 cell lysate stained with ARG55653 anti-REA antibody.