ARG66345
anti-PSA antibody [SQab1895]
anti-PSA antibody [SQab1895] for IHC-Formalin-fixed paraffin-embedded sections and Human
Overview
| Product Description | Recombinant Rabbit Monoclonal antibody [SQab1895] recognizes PSA |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | IHC-P |
| Host | Rabbit |
| Clonality | Monoclonal |
| Clone | SQab1895 |
| Isotype | IgG |
| Target Name | PSA |
| Antigen Species | Human |
| Immunogen | Synthetic peptide within aa. 150-250 of Human PSA. |
| Conjugation | Un-conjugated |
| Alternate Names | Prostate-specific antigen; Gamma-seminoprotein; APS; PSA; EC 3.4.21.77; Kallikrein-3; P-30 antigen; Semenogelase; hK3; Seminin; KLK2A1 |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | IHC-P: Antigen Retrieval: Heat mediated was performed using Tris/EDTA buffer (pH 9.0), primary antibody incubate at RT for 30 min. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purification with Protein A. |
| Buffer | PBS, 0.01% Sodium azide, 40% Glycerol and 0.05% BSA. |
| Preservative | 0.01% Sodium azide |
| Stabilizer | 40% Glycerol and 0.05% BSA |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | KLK3 |
| Gene Full Name | kallikrein-related peptidase 3 |
| Background | Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] |
| Function | Hydrolyzes semenogelin-1 thus leading to the liquefaction of the seminal coagulum. [UniProt] |
| Highlight | Related products: PSA antibodies; PSA ELISA Kits; PSA Duos / Panels; Anti-Rabbit IgG secondary antibodies; Related news: Cancer Pathology Markers (SQ clones) |
| Calculated MW | 29 kDa |
Images (1) Click the Picture to Zoom In
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ARG66345 anti-PSA antibody [SQab1895] IHC-P image
Immunohistochemistry: Formalin-fixed and paraffin-embedded prostate cancer tissue stained with ARG66345 anti-PSA antibody [SQab1895]. Antigen Retrieval: Heat mediated was performed using Tris/EDTA buffer (pH 9.0).
