ARG44467
anti-PHF6 antibody
anti-PHF6 antibody for IHC-Formalin-fixed paraffin-embedded sections,ICC/IF,Western blot,Flow cytometry and Human,Monkey,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes PHF6 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat, Mk |
| Tested Application | FACS, ICC/IF, IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Target Name | PHF6 |
| Antigen Species | Human |
| Immunogen | Human PHF6 recombinant protein |
| Conjugation | Un-conjugated |
| Alternate Names | PHF6; PHD Finger Protein 6; CENP-31; KIAA1823; PHD-Like Zinc Finger Protein; Centromere Protein 31; MGC14797; BFLS; BORJ; Borjeson-Forssman-Lehmann Syndrome |
Application Instructions
| Application Suggestion |
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| Application Note | The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 4% Trehalose. |
| Preservative | 0.05% Sodium azide |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | PHF6 |
| Gene Full Name | PHD Finger Protein 6 |
| Background | This gene is a member of the plant homeodomain (PHD)-like finger (PHF) family. It encodes a protein with two PHD-type zinc finger domains, indicating a potential role in transcriptional regulation, that localizes to the nucleolus. Mutations affecting the coding region of this gene or the splicing of the transcript have been associated with Borjeson-Forssman-Lehmann syndrome (BFLS), a disorder characterized by cognitive disability, epilepsy, hypogonadism, hypometabolism, obesity, swelling of subcutaneous tissue of the face, narrow palpebral fissures, and large ears. Alternate splicing results in multiple transcript variants, encoding different isoforms. |
| Function | Transcriptional regulator that associates with ribosomal RNA promoters and suppresses ribosomal RNA (rRNA) transcription. |
| Cellular Localization | Centromere, Chromosome, Kinetochore, Nucleus |
| Calculated MW | 41 kDa |
| PTM | Acetylation, Isopeptide bond, Phosphoprotein, Ubl conjugation |
Images (10) Click the Picture to Zoom In
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ARG44467 anti-PHF6 antibody IHC-P image
Immunohistochemistry: Human urothelial carcinoma stained with ARG44467 anti-PHF6 antibody at 2 μg/mL dilution.
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ARG44467 anti-PHF6 antibody ICC/IF image
Immunofluorescence: A549 stained with ARG44467 anti-PHF6 antibody at 5 μg/mL dilution.
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ARG44467 anti-PHF6 antibody WB image
Western blot: 293T, Jurkat and HeLa stained with ARG44467 anti-PHF6 antibody at 0.5 μg/mL dilution.
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ARG44467 anti-PHF6 antibody FACS image
Flow Cytometry: JK stained with ARG44467 anti-PHF6 antibody at 1 μg/10^6 cells dilution.
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ARG44467 anti-PHF6 antibody IHC-P image
Immunohistochemistry: Rat brain stained with ARG44467 anti-PHF6 antibody at 2 μg/mL dilution.
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ARG44467 anti-PHF6 antibody WB image
Western blot: C6 stained with ARG44467 anti-PHF6 antibody at 0.5 μg/mL dilution.
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ARG44467 anti-PHF6 antibody IHC-P image
Immunohistochemistry: Mouse brain stained with ARG44467 anti-PHF6 antibody at 2 μg/mL dilution.
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ARG44467 anti-PHF6 antibody WB image
Western blot: NIH/3T3 stained with ARG44467 anti-PHF6 antibody at 0.5 μg/mL dilution.
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ARG44467 anti-PHF6 antibody IHC-P image
Immunohistochemistry: Human glioblastoma stained with ARG44467 anti-PHF6 antibody at 2 μg/mL dilution.
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ARG44467 anti-PHF6 antibody WB image
Western blot: COS-7 stained with ARG44467 anti-PHF6 antibody at 0.5 μg/mL dilution.
