ARG42239
anti-NPY1R antibody
anti-NPY1R antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes NPY1R |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | NPY1R |
| Antigen Species | Human |
| Immunogen | Synthetic peptide of Human NPY1R. |
| Conjugation | Un-conjugated |
| Alternate Names | NPYR; Neuropeptide Y receptor type 1; NPY1-R |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| Positive Control | WB: Human fetal brain IHC-P: Human gastric cancer and human cervical cancer |
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| Observed Size | ~ 48 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | PBS (pH 7.4), 0.05% Sodium azide and 40% Glycerol. |
| Preservative | 0.05% Sodium azide |
| Stabilizer | 40% Glycerol |
| Concentration | 0.3 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | NPY1R |
| Gene Full Name | neuropeptide Y receptor Y1 |
| Background | This gene belongs to the G-protein-coupled receptor superfamily. The encoded transmembrane protein mediates the function of neuropeptide Y (NPY), a neurotransmitter, and peptide YY (PYY), a gastrointestinal hormone. The encoded receptor undergoes fast agonist-induced internalization through clathrin-coated pits and is subsequently recycled back to the cell membrane. Activation of Y1 receptors may result in mobilization of intracellular calcium and inhibition of adenylate cyclase activity. [provided by RefSeq, Aug 2013] |
| Function | Receptor for neuropeptide Y and peptide YY. The rank order of affinity of this receptor for pancreatic polypeptides is NPY > [Pro-34] PYY, PYY and [Leu-31, Pro-34] NPY > NPY (2-36) > [Ile-31, Gln-34] PP and PYY (3-36) > PP > NPY free acid. [UniProt] |
| Cellular Localization | Cell membrane; Multi-pass membrane protein. [UniProt] |
| Calculated MW | 44 kDa |
Images (3) Click the Picture to Zoom In
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ARG42239 anti-NPY1R antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human gasrtic cancer tissue stained with ARG42239 anti-NPY1R antibody (left) at 1:30 dilution, or the same antibody pre-incubated with synthetic peptide (right). (Original magnification: X200).
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ARG42239 anti-NPY1R antibody WB image
Western blot: 60 µg of Human fetal brain lysate stained with ARG42239 anti-NPY1R antibody at 1:500 dilution.
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ARG42239 anti-NPY1R antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human cervical cancer stained with ARG42239 anti-NPY1R antibody (left) at 1:30 dilution, or the same antibody pre-incubated with synthetic peptide (right). (Original magnification: X200).
