ARG22335
anti-IL2 Receptor beta antibody [5H4] (APC)
anti-IL2 Receptor beta antibody [5H4] (APC) for Flow cytometry and Mouse
Overview
| Product Description | APC-conjugated Rat Monoclonal antibody [5H4] recognizes IL2 Receptor beta |
|---|---|
| Tested Reactivity | Ms |
| Tested Application | FACS |
| Specificity | Mouse CD122 |
| Host | Rat |
| Clonality | Monoclonal |
| Clone | 5H4 |
| Isotype | IgG2a, kappa |
| Target Name | IL2 Receptor beta |
| Antigen Species | Mouse |
| Immunogen | Rat myeloma YB2/0 transfected with truncated IL-2Rβ cDNA (YB2/0-mβt-28) |
| Conjugation | APC |
| Alternate Names | P70-75; IL-2RB; IL-2 receptor subunit beta; p75; Interleukin-2 receptor subunit beta; CD122; CD antigen CD122; High affinity IL-2 receptor subunit beta; IL-2R subunit beta; p70-75; IL15RB |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Buffer | PBS, 0.1% Sodium azide and Sucrose. |
| Preservative | 0.1% Sodium azide |
| Stabilizer | Sucrose |
| Concentration | 0.1 mg/ml |
| Storage Instruction | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # P16297 Mouse Interleukin-2 receptor subunit beta |
|---|---|
| Gene Symbol | IL2RB |
| Gene Full Name | interleukin 2 receptor, beta chain |
| Background | The interleukin 2 receptor, which is involved in T cell-mediated immune responses, is present in 3 forms with respect to ability to bind interleukin 2. The low affinity form is a monomer of the alpha subunit and is not involved in signal transduction. The intermediate affinity form consists of an alpha/beta subunit heterodimer, while the high affinity form consists of an alpha/beta/gamma subunit heterotrimer. Both the intermediate and high affinity forms of the receptor are involved in receptor-mediated endocytosis and transduction of mitogenic signals from interleukin 2. The protein encoded by this gene represents the beta subunit and is a type I membrane protein. [provided by RefSeq, Jul 2008] |
| Function | Receptor for interleukin-2. This beta subunit is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2. [UniProt] |
| Calculated MW | 61 kDa |
