ARG23329
anti-IL13 Receptor alpha 1 antibody [B-K19] (Biotin)
anti-IL13 Receptor alpha 1 antibody [B-K19] (Biotin) for IHC-Formalin-fixed paraffin-embedded sections and Human
Overview
| Product Description | Biotin-conjugated Mouse Monoclonal antibody [B-K19] recognizes IL13 Receptor alpha 1 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | IHC-P |
| Specificity | This antibody recognizes the IL-13 receptor a1 (IL-13 Ra1). |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | B-K19 |
| Isotype | IgG1 |
| Target Name | IL13 Receptor alpha 1 |
| Antigen Species | Human |
| Immunogen | IL-13Ra1 transfected CHO cell line |
| Conjugation | Biotin |
| Alternate Names | CD antigen CD213a1; Interleukin-13 receptor subunit alpha-1; CD213A1; IL-13R-alpha-1; CT19; IL-13R subunit alpha-1; IL-13Ra; IL-13 receptor subunit alpha-1; IL-13RA1; Cancer/testis antigen 19; NR4 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Buffer | PBS, 0.1% Sodium azide and 1% BSA. |
| Preservative | 0.1% Sodium azide |
| Stabilizer | 1% BSA |
| Storage Instruction | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # P78552 Human Interleukin-13 receptor subunit alpha-1 |
|---|---|
| Gene Symbol | IL13RA1 |
| Gene Full Name | interleukin 13 receptor, alpha 1 |
| Background | The protein encoded by this gene is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha, a subunit shared by IL13 and IL4 receptors. This subunit serves as a primary IL13-binding subunit of the IL13 receptor, and may also be a component of IL4 receptors. This protein has been shown to bind tyrosine kinase TYK2, and thus may mediate the signaling processes that lead to the activation of JAK1, STAT3 and STAT6 induced by IL13 and IL4. [provided by RefSeq, Jul 2008] |
| Function | Binds with low affinity to interleukin-13 (IL13). Together with IL4RA can form a functional receptor for IL13. Also serves as an alternate accessory protein to the common cytokine receptor gamma chain for interleukin-4 (IL4) signaling, but cannot replace the function of IL2RG in allowing enhanced interleukin-2 (IL2) binding activity. [UniProt] |
| Calculated MW | 49 kDa |
