ARG44846
anti-ID4 antibody
anti-ID4 antibody for IHC-Formalin-fixed paraffin-embedded sections and Human
Overview
| Product Description | Mouse Monoclonal antibody recognizes ID4 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | IHC-P |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG1 |
| Target Name | ID4 |
| Antigen Species | Human |
| Epitope | MKAVSPVRPS GRKAPSGCGG GELALRCLAE HGHSLGGSAA AAAAAAAARC KAAEAAADEP ALCLQCDMND CYSRLRRLVP TIPPNKKVSK VEILQHVIDY ILDLQLALET HPALLRQPPP PAPPHHPAGT CPAAPPRTPL TALNTDPAGA VNKQGDSILC R |
| Conjugation | Un-conjugated |
| Alternate Names | ID4; Inhibitor Of DNA Binding 4; BHLHb27; Inhibitor Of Differentiation 4; Inhibitor Of DNA Binding 4, Dominant Negative Helix-Loop-Helix Protein; Class B Basic Helix-Loop-Helix Protein 27; DNA-Binding Protein Inhibitor ID-4; Inhibitor Of DNA Binding 4, HLH Protein; BHLHB27; IDB4 |
Application Instructions
| Application Suggestion |
|
||||
|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Protein A purification |
| Buffer | PBS with 0.09% sodium azide |
| Preservative | 0.09% sodium azide |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # P47928 Human DNA-binding protein inhibitor ID-4 |
|---|---|
| Gene Symbol | ID4 |
| Gene Full Name | Inhibitor Of DNA Binding 4 |
| Background | This gene encodes a member of the inhibitor of DNA binding (ID) protein family. The encoded protein lacks DNA binding ability, and instead regulates gene expression through binding to and inhibiting basic helix-loop-helix transcription factors. This protein has been implicated in the regulation of diverse cellular processes that play a role in development and tumorigenesis. [provided by RefSeq, Aug 2017] |
| Function | Transcriptional regulator (lacking a basic DNA binding domain) which negatively regulates the basic helix-loop-helix (bHLH) transcription factors by forming heterodimers and inhibiting their DNA binding and transcriptional activity. Implicated in regulating a variety of cellular processes, including cellular growth, senescence, differentiation, apoptosis, angiogenesis, and neoplastic transformation. [Uniprot] |
| Cellular Localization | Nucleus. [Uniprot] |
Images (1) Click the Picture to Zoom In
-
ARG44846 anti-ID4 antibody IHC-P image
Immunohistochemistry: Human testis stained with ARG44846 anti-ID4 antibody at 10 µg/mL dilution.
