ARG22396
anti-HVEM / TR2 antibody [CW2]
anti-HVEM / TR2 antibody [CW2] for ICC/IF,Western blot and Human
Overview
| Product Description | Mouse Monoclonal antibody [CW2] recognizes HVEM / TR2 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | ICC/IF, WB |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | CW2 |
| Isotype | IgG1, kappa |
| Target Name | HVEM / TR2 |
| Antigen Species | Human |
| Immunogen | Human HVEM / TR2 |
| Conjugation | Un-conjugated |
| Alternate Names | Herpes virus entry mediator A; HVEM; Tumor necrosis factor receptor-like 2; HVEA; CD antigen CD270; CD270; Tumor necrosis factor receptor superfamily member 14; LIGHTR; HveA; Herpesvirus entry mediator A; ATAR; TR2 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purification with Protein G. |
| Buffer | PBS (pH 7.4) |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q92956 Human Tumor necrosis factor receptor superfamily member 14 |
|---|---|
| Gene Symbol | TNFRSF14 |
| Gene Full Name | tumor necrosis factor receptor superfamily, member 14 |
| Background | This gene encodes a member of the TNF (tumor necrosis factor) receptor superfamily. The encoded protein functions in signal transduction pathways that activate inflammatory and inhibitory T-cell immune response. It binds herpes simplex virus (HSV) viral envelope glycoprotein D (gD), mediating its entry into cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014] |
| Function | Receptor for BTLA. Receptor for TNFSF14/LIGHT and homotrimeric TNFSF1/lymphotoxin-alpha. Involved in lymphocyte activation. Plays an important role in HSV pathogenesis because it enhanced the entry of several wild-type HSV strains of both serotypes into CHO cells, and mediated HSV entry into activated human T-cells. [UniProt] |
| Highlight | Related products: HVEM antibodies; HVEM ELISA Kits; Anti-Mouse IgG secondary antibodies; Related news: New PD-1 ELISA Kit, excellent for preclinical studies or pharmatheutical development Why anti-PD-1/PD-L1 therapy doesn’t work? Time to fight cancer by NK cells |
| Calculated MW | 30 kDa |
| PTM | N-glycosylated. |
Images (1) Click the Picture to Zoom In
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ARG22396 anti-HVEM / TR2 antibody [CW2] WB image
Western blot: 0.1 µg/cm of HVEM Recombinant Protein stained with ARG22396 anti-HVEM / TR2 antibody [CW2].
