ARG42638
anti-GSDMC antibody
anti-GSDMC antibody for ICC/IF,Western blot and Human,Mouse
Overview
| Product Description | Rabbit Polyclonal antibody recognizes GSDMC |
|---|---|
| Tested Reactivity | Hu, Ms |
| Tested Application | ICC/IF, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | GSDMC |
| Antigen Species | Human |
| Immunogen | Recombinant fusion protein corresponding to aa. 1-100 of Human GSDMC (NP_113603.1). |
| Conjugation | Un-conjugated |
| Alternate Names | MLZE; Melanoma-derived leucine zipper-containing extranuclear factor; Gasdermin-C |
Application Instructions
| Application Suggestion |
|
||||||
|---|---|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| Positive Control | HeLa | ||||||
| Observed Size | ~ 58 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | GSDMC |
| Gene Full Name | gasdermin C |
| Function | The N-terminal moiety promotes pyroptosis. May be acting by homooligomerizing within the membrane and forming pores (PubMed:27281216). The physiological relevance of this observation is unknown (Probable). [UniProt] |
| Highlight | Related news: Solutions for studying PANoptosis & PANoptosome |
| Calculated MW | 58 kDa |
Images (2) Click the Picture to Zoom In
-
ARG42638 anti-GSDMC antibody ICC/IF image
Immunofluorescence: L929 cells stained with ARG42638 anti-GSDMC antibody at 1:100 dilution. DAPI (blue) for nuclear staining.
-
ARG42638 anti-GSDMC antibody WB image
Western blot: 25 µg of HeLa cell lysate stained with ARG42638 anti-GSDMC antibody at 1:3000 dilution.
