ARG58728
anti-GALNT2 antibody
anti-GALNT2 antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes GALNT2 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | ICC/IF, IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | GALNT2 |
| Antigen Species | Human |
| Immunogen | Recombinant fusion protein corresponding to aa. 442-571 of Human GALNT2 (NP_004472.1). |
| Conjugation | Un-conjugated |
| Alternate Names | Protein-UDP acetylgalactosaminyltransferase 2; EC 2.4.1.41; pp-GaNTase 2; GalNAc-T2; Polypeptide N-acetylgalactosaminyltransferase 2; UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 2; Polypeptide GalNAc transferase 2 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| Observed Size | 65 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q10471 Human Polypeptide N-acetylgalactosaminyltransferase 2 Swiss-port # Q6PB93 Mouse Polypeptide N-acetylgalactosaminyltransferase 2 |
|---|---|
| Gene Symbol | GALNT2 |
| Gene Full Name | polypeptide N-acetylgalactosaminyltransferase 2 |
| Background | This gene encodes a member of the glycosyltransferase 2 protein family. Members of this family initiate mucin-type O-glycoslation of peptides in the Golgi apparatus. The encoded protein may be involved in O-linked glycosylation of the immunoglobulin A1 hinge region. This gene may influence triglyceride levels, and may be involved Type 2 diabetes, as well as several types of cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014] |
| Function | Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Has a broad spectrum of substrates for peptides such as EA2, Muc5AC, Muc1a, Muc1b. Probably involved in O-linked glycosylation of the immunoglobulin A1 (IgA1) hinge region. [UniProt] |
| Cellular Localization | Golgi apparatus, Golgi stack membrane, Single-pass type II membrane protein, Secreted. [UniProt] |
| Calculated MW | 65 kDa |
Images (2) Click the Picture to Zoom In
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ARG58728 anti-GALNT2 antibody ICC/IF image
Immunofluorescence: HeLa cells stained with ARG58728 anti-GALNT2 antibody.
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ARG58728 anti-GALNT2 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Rat brain stained with ARG58728 anti-GALNT2 antibody at 1:100 dilution.
