ARG67032
anti-FOXL2 / BPES antibody [SQab30327]
anti-FOXL2 / BPES antibody [SQab30327] for IHC-Formalin-fixed paraffin-embedded sections and Human
Overview
| Product Description | Recombinant rabbit Monoclonal antibody [SQab30327] recognizes FOXL2 / BPES |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | IHC-P |
| Host | Rabbit |
| Clonality | Monoclonal |
| Clone | SQab30327 |
| Isotype | IgG |
| Target Name | FOXL2 / BPES |
| Antigen Species | Human |
| Immunogen | Recombinant protein of Human FOXL2. |
| Conjugation | Un-conjugated |
| Protein Full Name | Forkhead box protein L2 |
| Alternate Names | FOXL2, Forkhead Box L2, BPES, Forkhead Box Protein L2, BPES, Forkhead Transcription Factor FOXL2, PINTO, PFRK, POF3 |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| Positive Control | ovarian granulosa cell |
Properties
| Form | Liquid |
|---|---|
| Purification | Purification with Protein A. |
| Buffer | PBS, 0.01% Sodium azide, 40% Glycerol and 0.05%BSA. |
| Preservative | 0.01% Sodium azide |
| Stabilizer | 40% Glycerol and 0.05%BSA |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | FOXL2 |
| Gene Full Name | Forkhead Box L2 |
| Background | This gene encodes a forkhead transcription factor. The protein contains a fork-head DNA-binding domain and may play a role in ovarian development and function. Expansion of a polyalanine repeat region and other mutations in this gene are a cause of blepharophimosis syndrome and premature ovarian failure 3. [provided by RefSeq, Jul 2016] |
| Function | Transcriptional regulator. Critical factor essential for ovary differentiation and maintenance, and repression of the genetic program for somatic testis determination. Prevents trans-differentiation of ovary to testis through transcriptional repression of the Sertoli cell-promoting gene SOX9. [UniProt] |
| Cellular Localization | Nucleus |
| Calculated MW | 39 kDa |
| PTM | Isopeptide bond, Phosphoprotein, Ubl conjugation [UniProt] |
Images (1) Click the Picture to Zoom In
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ARG67032 anti-FOXL2 / BPES antibody [SQab30327] IHC-P image
Immunohistochemistry: Formalin-fixed and paraffin-embedded ovarian granulosa cell stained with ARG67032 anti-FOXL2 / BPES antibody [SQab30327].
