ARG45273
anti-FAM60A antibody
anti-FAM60A antibody for Flow cytometry,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Rat
Overview
| Product Description | Polyclonal antibody recognizes FAM60A |
|---|---|
| Tested Reactivity | Hu, Rat |
| Tested Application | FACS, ICC/IF, IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | FAM60A |
| Antigen Species | Human |
| Immunogen | Recombinant protein containing to human FAM60A. |
| Conjugation | Un-conjugated |
| Alternate Names | SINHCAF; SIN3-HDAC Complex Associated Factor; C12orf14; FAM60A; TERA; SIN3-HDAC Complex-Associated Factor; Tera Protein Homolog; Protein FAM60A; Family With Sequence Similarity 60, Member A; Family With Sequence Similarity 60 Member A; Chromosome 12 Open Reading Frame 14; L4 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||||
| Observed Size | 28-30 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | SINHCAF |
| Gene Full Name | SIN3-HDAC Complex Associated Factor |
| Background | Involved in negative regulation of cell migration. Part of Sin3-type complex. [provided by Alliance of Genome Resources, Nov 2024] |
| Function | Subunit of the Sin3 deacetylase complex (Sin3/HDAC), this subunit is important for the repression of genes encoding components of the TGF-beta signaling pathway (PubMed:22865885, PubMed:22984288). Core component of a SIN3A complex (composed of at least SINHCAF, SIN3A, HDAC1, SAP30, RBBP4, OGT and TET1) present in embryonic stem (ES) cells. Promotes the stability of SIN3A and its presence on chromatin and is essential for maintaining the potential of ES cells to proliferate rapidly, while ensuring a short G1-phase of the cell cycle, thereby preventing premature lineage priming . [UniProt] |
| Cellular Localization | Nucleus. [UniProt] |
| Calculated MW | 25 kDa |
Images (5) Click the Picture to Zoom In
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ARG45273 anti-FAM60A antibody IHC-P image
Immunohistochemistry: Human prostate adenocarcinoma stained with ARG45273 anti-FAM60A antibody at 2 μg/ml dilution.
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ARG45273 anti-FAM60A antibody ICC/IF image
Immunofluorescence: A549 stained with ARG45273 anti-FAM60A antibody at 5 ug/ml dilution.
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ARG45273 anti-FAM60A antibody WB image
Western blot: MOLT-4 and SH-SY5Y stained with ARG45273 anti-FAM60A antibody at 0.5 μg/ml dilution.
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ARG45273 anti-FAM60A antibody FACS image
Flow Cytometry: U937 stained with ARG45273 anti-FAM60A antibody at 1 µg/10^6 cells dilution.
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ARG45273 anti-FAM60A antibody IHC-P image
Immunohistochemistry: Rat brain stained with ARG45273 anti-FAM60A antibody at 2 μg/ml dilution.
