ARG43834
anti-DLAT antibody
anti-DLAT antibody for ICC/IF,Immunoprecipitation,Western blot and Human,Mouse,Rat,Hamster
Controls and Markers antibody; Metabolism antibody; Signaling Transduction antibody
Overview
Product Description | Rabbit Polyclonal antibody recognizes DLAT. |
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Tested Reactivity | Hu, Ms, Rat, Hm |
Tested Application | ICC/IF, IP, WB |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | IgG |
Target Name | DLAT |
Antigen Species | Human |
Immunogen | Synthetic peptide of human DLAT. |
Conjugation | Un-conjugated |
Alternate Names | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial; PDC-E2; Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex; M2 antigen complex 70 kDa subunit; EC 2.3.1.12; PBC; Pyruvate dehydrogenase complex component E2; DLTA; 70 kDa mitochondrial autoantigen of primary biliary cirrhosis; PDCE2 |
Application Instructions
Application Suggestion |
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Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
Form | Liquid |
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Purification | Affinity purified |
Buffer | Tris-Glycine (pH 7.4) with 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
Preservative | 0.01% Sodium azide |
Stabilizer | 40% Glycerol and 0.05% BSA |
Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
Database Links | |
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Gene Symbol | DLAT |
Gene Full Name | dihydrolipoamide S-acetyltransferase |
Background | The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). |
Function | The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle. [UniProt] |
Cellular Localization | Mitochondrion matrix. |
Research Area | Controls and Markers antibody; Metabolism antibody; Signaling Transduction antibody |
PTM | Delipoylated at Lys-132 and Lys-259 by SIRT4, delipoylation decreases the PHD complex activity. |
Images (3) Click the Picture to Zoom In
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ARG43834 anti-DLAT antibody WB image
Western blot: : CHO-K1, C6, Rat Brain and Ramos stained with ARG43834 anti-DLAT antibody
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ARG43834 anti-DLAT antibody ICC/IF image
Immunofluorescence: Hela were stained with ARG43834 anti-DLAT antibody.
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ARG43834 anti-DLAT antibody WB image
Western blot: Mouse Heart stained with ARG43834 anti-DLAT antibody