ARG40215
anti-Cadherin 16 antibody
anti-Cadherin 16 antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes Cadherin 16 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | ICC/IF, IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | Cadherin 16 |
| Antigen Species | Human |
| Immunogen | Recombinant fusion protein corresponding to aa. 19-230 of Human Cadherin 16. (NP_004053.1) |
| Conjugation | Un-conjugated |
| Alternate Names | Kidney-specific cadherin; Ksp-cadherin; Cadherin-16 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| Positive Control | HepG2 | ||||||||
| Observed Size | 110 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | CDH16 |
| Gene Full Name | cadherin 16, KSP-cadherin |
| Background | This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. Mapped to a previously identified cluster of cadherin genes on chromosome 16q22.1, the gene localizes with superfamily members CDH1, CDH3, CDH5, CDH8 and CDH11. The protein consists of an extracellular domain containing 6 cadherin domains, a transmembrane region and a truncated cytoplasmic domain but lacks the prosequence and tripeptide HAV adhesion recognition sequence typical of most classical cadherins. Expression is exclusively in kidney, where the protein functions as the principal mediator of homotypic cellular recognition, playing a role in the morphogenic direction of tissue development. Alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Mar 2011] |
| Function | Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. [UniProt] |
| Cellular Localization | Cell membrane; Single-pass type I membrane protein. [UniProt] |
| Calculated MW | 90 kDa |
Images (3) Click the Picture to Zoom In
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ARG40215 anti-Cadherin 16 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Rat brain stained with ARG40215 anti-Cadherin 16 antibody at 1:100 dilution.
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ARG40215 anti-Cadherin 16 antibody WB image
Western blot: 25 µg of HepG2 cell lysate stained with ARG40215 anti-Cadherin 16 antibody at 1:1000 dilution.
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ARG40215 anti-Cadherin 16 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Mouse brain stained with ARG40215 anti-Cadherin 16 antibody at 1:100 dilution.
