ARG44596

anti-CLEC4C / BDCA2 antibody [15E3] (APC)

anti-CLEC4C / BDCA2 antibody [15E3] (APC) for Flow cytometry and Human

Overview

Product Description APC-conjugated Mouse Monoclonal antibody recognizes CLEC4C / BDCA2
Tested Reactivity Hu
Tested Application FACS
Host Mouse
Clonality Monoclonal
Clone 15E3
Isotype IgG1 kappa
Target Name CLEC4C / BDCA2
Antigen Species Human
Conjugation APC
Alternate Names CLEC4C; C-Type Lectin Domain Family 4 Member C; BDCA2; HECL; DLEC; CLECSF11; CLECSF7; CD303; C-Type (Calcium Dependent, Carbohydrate-Recognition Domain) Lectin, Superfamily Member 7; C-Type Lectin Superfamily Member 7; Dendritic Lectin; BDCA-2; C-Type (Calcium Dependent, Carbohydrate-Recognition Domain) Lectin, Superfamily Member 11; C-Type Lectin Domain Family 4, Member C; Blood Dendritic Cell Antigen 2 Protein; Blood Dendritic Cell Antigen 2; Dendritic Cell Lectin B; CD303 Antigen; PRO34150

Application Instructions

Application Suggestion
Tested Application Dilution
FACS10 µl / 100 µl or 10^6 cells
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Purified antibody is conjugated with activated allophycocyanin (APC), and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
Buffer PBS (pH 7.4) and 15 mM Sodium azide
Preservative 15 mM Sodium azide
Storage Instruction Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 170482 Human CLEC4C

Swiss-port # Q8WTT0 Human C-type lectin domain family 4 member C

Gene Symbol CLEC4C
Gene Full Name C-Type Lectin Domain Family 4 Member C
Background This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type 2 transmembrane protein may play a role in dendritic cell function. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
Function May act as a signaling receptor that activates protein-tyrosine kinases and mobilizes intracellular calcium. [UniProt]
Cellular Localization Cell membrane, Membrane. [UniProt]
Calculated MW 25 kDa
PTM Disulfide bond, Glycoprotein. [UniProt]

Images (1) Click the Picture to Zoom In

  • ARG44596 anti-CLEC4C / BDCA2 antibody [15E3] (APC) FACS image

    Flow Cytometry: Human peripheral whole blood stained with ARG44596 anti-CLEC4C / BDCA2 antibody [15E3] (APC) at 10 μl/ 100 μl dilution.