ARG57340
anti-CHD2 antibody
anti-CHD2 antibody for Western blot and Human,Mouse,Rat
1
Overview
| Product Description | Rabbit Polyclonal antibody recognizes CHD2 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | CHD2 |
| Antigen Species | Human |
| Immunogen | Recombinant Protein of Human CHD2. |
| Conjugation | Un-conjugated |
| Alternate Names | ATP-dependent helicase CHD2; EC 3.6.4.12; EEOC; Chromodomain-helicase-DNA-binding protein 2; CHD-2 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| Positive Control | HeLa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # E9PZM4 Mouse Chromodomain-helicase-DNA-binding protein 2 Swiss-port # O14647 Human Chromodomain-helicase-DNA-binding protein 2 |
|---|---|
| Gene Symbol | CHD2 |
| Gene Full Name | chromodomain helicase DNA binding protein 2 |
| Background | The CHD family of proteins is characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. CHD genes alter gene expression possibly by modification of chromatin structure thus altering access of the transcriptional apparatus to its chromosomal DNA template. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
| Function | DNA-binding helicase that specifically binds to the promoter of target genes, leading to chromatin remodeling, possibly by promoting deposition of histone H3.3. Involved in myogenesis via interaction with MYOD1: binds to myogenic gene regulatory sequences and mediates incorporation of histone H3.3 prior to the onset of myogenic gene expression, promoting their expression (By similarity). [UniProt] |
| Calculated MW | 211 kDa |
Images (1) Click the Picture to Zoom In
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ARG57340 anti-CHD2 antibody WB image
Western blot: HeLa cell lysate stained with ARG57340 anti-CHD2 antibody.
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Review for anti-CHD2 antibody
Application：WB
Sample：293T
Sample Loading Amount：30 µg
Primary Antibody Dilution Factor：1:500
Primary Antibody Incubation Time：overnight
Primary Antibody Incubation Temperature：4 ºC
