ARG63835
anti-CFC1 / Cripto 1 antibody
anti-CFC1 / Cripto 1 antibody for IHC-Formalin-fixed paraffin-embedded sections and Mouse
Signaling Transduction antibody
Overview
| Product Description | Goat Polyclonal antibody recognizes CFC1 / Cripto 1 |
|---|---|
| Tested Reactivity | Ms |
| Predict Reactivity | Hu, Rat |
| Tested Application | IHC-P |
| Host | Goat |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | CFC1 / Cripto 1 |
| Antigen Species | Human |
| Immunogen | HFTGRYCEHDQRRSEC |
| Conjugation | Un-conjugated |
| Alternate Names | Cryptic family protein 1; HTX2; CRYPTIC; DTGA2; CFC1B; Cryptic protein |
Application Instructions
| Application Suggestion |
|
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|---|---|---|---|---|---|
| Application Note | IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Buffer | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 0.5% BSA |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Background | This gene encodes a member of the epidermal growth factor (EGF)- Cripto, Frl-1, and Cryptic (CFC) family, which are involved in signalling during embryonic development. Proteins in this family share a variant EGF-like motif, a conserved cysteine-rich domain, and a C-terminal hydrophobic region. The protein encoded by this gene is necessary for patterning the left-right embryonic axis. Mutations in this gene are associated with defects in organ development, including autosomal visceral heterotaxy and congenital heart disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012] |
| Research Area | Signaling Transduction antibody |
| Calculated MW | 25 kDa |
| PTM | N-glycosylated. |
Images (1) Click the Picture to Zoom In
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ARG63835 anti-CFC1 / Cripto 1 antibody IHC-P image
Immunohistochemistry: Paraffin embedded Mouse Embryo Liver. (Steamed antigen retrieval with citrate buffer pH 6) stained with ARG63835 anti-CFC1 / Cripto 1 antibody at 2 µg/ml dilution followed by HRP-staining.
