ARG53906
anti-CD81 antibody [M38] (PE)
anti-CD81 antibody [M38] (PE) for Flow cytometry and Human,Cat,Rabbit
Immune System antibody; Microbiology and Infectious Disease antibody
Overview
Product Description | PE-conjugated Mouse Monoclonal antibody [M38] recognizes CD81 |
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Tested Reactivity | Hu, Cat, Rb |
Tested Application | FACS |
Specificity | The clone M38 reacts with CD81, a 25 kDa member of the tetraspanin family, expressed on majority of cells. |
Host | Mouse |
Clonality | Monoclonal |
Clone | M38 |
Isotype | IgG1 |
Target Name | CD81 |
Antigen Species | Human |
Immunogen | MOLT-4 (human T-ALL cell line) |
Conjugation | PE |
Alternate Names | CD antigen CD81; TAPA1; Tspan-28; S5.7; CD81 antigen; Target of the antiproliferative antibody 1; Tetraspanin-28; 26 kDa cell surface protein TAPA-1; CVID6; TSPAN28 |
Application Instructions
Application Suggestion |
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Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
Form | Liquid |
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Purification Note | The purified antibody is conjugated with R-Phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary. |
Buffer | PBS, 15 mM Sodium azide and 0.2% (w/v) high-grade protease free BSA |
Preservative | 15 mM Sodium azide |
Stabilizer | 0.2% (w/v) high-grade protease free BSA |
Storage Instruction | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
Database Links | |
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Gene Symbol | CD81 |
Gene Full Name | CD81 molecule |
Background | CD81 (TAPA-1), a member of the tetraspanin family, is expressed on virtually all nucleated cells, but above all on germinal center B cells. CD81 forms complexes with other tetraspanin proteins, integrins, coreceptors, MHC class I and II molecules, and influences adhesion, morphology, activation, proliferation and differentiation of B, T and other cells – e.g. in muscles CD81 promotes cell fusion and myotube maintenance. CD81 has been also identified as a receptor for the hepatitis C virus. |
Function | May play an important role in the regulation of lymphoma cell growth. Interacts with a 16-kDa Leu-13 protein to form a complex possibly involved in signal transduction. May act as the viral receptor for HCV. [UniProt] |
Highlight | Related products: CD81 antibodies; Anti-Mouse IgG secondary antibodies; Related news: Tools for studying Exosomes |
Research Area | Immune System antibody; Microbiology and Infectious Disease antibody |
Calculated MW | 26 kDa |
PTM | Not glycosylated. |
Images (2) Click the Picture to Zoom In
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ARG53906 anti-CD81 antibody [M38] (PE) FACS image
Flow Cytometry: Human peripheral whole blood stained with ARG53906 anti-CD81 antibody [M38] (PE) (20 µl reagent / 100 µl of peripheral whole blood).
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ARG53906 anti-CD81 antibody [M38] (PE) FACS image
Flow Cytometry: Separation of human lymphocytes (red-filled) from neutrophil granulocytes (black-dashed). Human peripheral whole blood stained with ARG53906 anti-CD81 antibody [M38] (PE) (20 µl reagent / 100 µl of peripheral whole blood).
Clone References