ARG21362
anti-CD43 antibody [DF-T1] (APC)
anti-CD43 antibody [DF-T1] (APC) for Flow cytometry,ICC/IF,IHC-Frozen sections,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
Overview
| Product Description | APC-conjugated Mouse Monoclonal antibody [DF-T1] recognizes CD43 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | FACS, ICC/IF, IHC-Fr, IHC-P, WB |
| Specificity | Human CD43. |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | DF-T1 |
| Isotype | IgG1, kappa |
| Target Name | CD43 |
| Antigen Species | Human |
| Immunogen | KG-1 cells |
| Conjugation | APC |
| Alternate Names | LSN; CD43; GALGP; GPL115 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Buffer | PBS, 0.1% Sodium azide and Sucrose. |
| Preservative | 0.1% Sodium azide |
| Stabilizer | Sucrose |
| Storage Instruction | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | SPN |
| Gene Full Name | sialophorin |
| Background | The protein encoded by this gene is a major sialoglycoprotein found on the surface of thymocytes, T lymphocytes, monocytes, granulocytes, and some B lymphocytes. It may be part of a physiologic ligand-receptor complex involved in T-cell activation. During T-cell activation, this protein is actively removed from the T-cell-APC (antigen-presenting cell) contact site, suggesting a negative regulatory role in adaptive immune response. [provided by RefSeq, Sep 2011] |
| Function | One of the major glycoproteins of thymocytes and T lymphocytes. Plays a role in the physicochemical properties of the T-cell surface and in lectin binding. Presents carbohydrate ligands to selectins. Has an extended rodlike structure that could protrude above the glycocalyx of the cell and allow multiple glycan chains to be accessible for binding. Is a counter-receptor for SN/Siglec-1 (By similarity). During T-cell activation is actively removed from the T-cell-APC (antigen-presenting cell) contact site thus suggesting a negative regulatory role in adaptive immune response (By similarity). [UniProt] |
| Calculated MW | 40 kDa |
Images (1) Click the Picture to Zoom In
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ARG21362 anti-CD43 antibody [DF-T1] (APC) FACS image
Flow Cytometry: Human peripheral blood lymphocytes stained with ARG21362 anti-CD43 antibody [DF-T1] (APC) and ARG21258 anti-CD19 antibody [SJ25-C1] (FITC).
