ARG66206
anti-CD21 antibody [SQab1728]
anti-CD21 antibody [SQab1728] for Flow cytometry,IHC-Formalin-fixed paraffin-embedded sections and Human
Publication1
Overview
| Product Description | Recombinant Rabbit Monoclonal antibody [SQab1728] recognizes CD21 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | FACS, IHC-P |
| Host | Rabbit |
| Clonality | Monoclonal |
| Clone | SQab1728 |
| Isotype | IgG |
| Target Name | CD21 |
| Antigen Species | Human |
| Immunogen | Synthetic peptide around the C‐terminus of CD21. |
| Conjugation | Un-conjugated |
| Alternate Names | Cr2; Complement C3d receptor; C3DR; CD21; CD antigen CD21; Complement receptor type 2; SLEB9; CR; CVID7; Epstein-Barr virus receptor; EBV receptor |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|---|---|
| Application Note | IHC-P: Antigen retrieval: Heat mediated was performed using Tris/EDTA buffer (pH 9.0). * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | PBS, 0.01% Sodium azide, 40% Glycerol and 0.05% BSA. |
| Preservative | 0.01% Sodium azide |
| Stabilizer | 40% Glycerol and 0.05% BSA |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | CR2 |
| Gene Full Name | complement component (3d/Epstein Barr virus) receptor 2 |
| Background | This gene encodes a membrane protein, which functions as a receptor for Epstein-Barr virus (EBV) binding on B and T lymphocytes. Genetic variations in this gene are associated with susceptibility to systemic lupus erythematosus type 9 (SLEB9). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009] |
| Function | Receptor for complement C3Dd, for the Epstein-Barr virus on human B-cells and T-cells and for HNRPU. Participates in B lymphocytes activation. [UniProt] |
| Highlight | Related products: CD21 antibodies; CD21 ELISA Kits; Related news: Cancer Pathology Markers (SQ clones) |
| Calculated MW | 113 kDa |
Images (3) Click the Picture to Zoom In
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ARG66206 anti-CD21 antibody [SQab1728] FACS image
Flow Cytometry: Ramos cells were fixed with 4% paraformaldehyde (10 min) and then permeabilized with 0.1% TritonX-100 for 15 min. The cells were then stained with ARG66206 anti-CD21 antibody [SQab1728] (red) at 1:10 dilution in 1x PBS/1% BSA for 30 min at room temperture, followed by Alexa Fluor® 488 labelled secondary antibody. Unlabelled sample (black) was used as a control.
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ARG66206 anti-CD21 antibody [SQab1728] IHC-P image
Immunohistochemistry: Formalin‐fixed and paraffin‐embedded Human spleen tissue stained with ARG66206 anti-CD21 antibody [SQab1728] at 1:200 dilution.
Antigen retrieval: Heat mediated was performed using Tris/EDTA buffer pH 9.0
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ARG66206 anti-CD21 antibody [SQab1728] IHC-P image
Immunohistochemistry: Formalin‐fixed and paraffin‐embedded Human appendix tissue stained with ARG66206 anti-CD21 antibody [SQab1728] at 1:200 dilution.
Antigen retrieval: Heat mediated was performed using Tris/EDTA buffer pH 9.0
Specific References
Tertiary lymphoid organs in the inflammatory myopathy associated with PD-1 inhibitors.
IHC-P / Human
