ARG22372
anti-CD206 / MMR antibody
anti-CD206 / MMR antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat,Pig
Immune System antibody; M1/M2/TAM Marker antibody; Macrophage Marker antibody; M2 Macrophage Marker antibody
Overview
Product Description | Rabbit Polyclonal antibody recognizes CD206 / MMR |
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Tested Reactivity | Hu, Ms, Rat, Pig |
Tested Application | ICC/IF, IHC-P, WB |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | IgG |
Target Name | CD206 / MMR |
Antigen Species | Human |
Immunogen | KLH-conjugated synthetic peptide from Human CD206 / MMR. |
Conjugation | Un-conjugated |
Alternate Names | CLEC13D; C-type lectin domain family 13 member D; Macrophage mannose receptor 1-like protein 1; C-type lectin domain family 13 member D-like; MMR; CLEC13DL; CD206; Macrophage mannose receptor 1; bA541I19.1; CD antigen CD206; MRC1L1 |
Application Instructions
Application Suggestion |
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Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
Form | Liquid |
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Purification | Affinity purification with immunogen. |
Buffer | PBS and 0.02% Sodium azide. |
Preservative | 0.02% Sodium azide |
Concentration | 0.5 mg/ml |
Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
Database Links | |
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Gene Symbol | MRC1 |
Gene Full Name | mannose receptor, C type 1 |
Background | The recognition of complex carbohydrate structures on glycoproteins is an important part of several biological processes, including cell-cell recognition, serum glycoprotein turnover, and neutralization of pathogens. CD206 / MMR is a type I membrane receptor that mediates the endocytosis of glycoproteins by macrophages. The protein has been shown to bind high-mannose structures on the surface of potentially pathogenic viruses, bacteria, and fungi so that they can be neutralized by phagocytic engulfment. [provided by RefSeq, Sep 2015] |
Function | CD206 / MMR mediates the endocytosis of glycoproteins by macrophages. Binds both sulfated and non-sulfated polysaccharide chains. (Microbial infection) Acts as phagocytic receptor for bacteria, fungi and other pathogens. (Microbial infection) Acts as a receptor for Dengue virus envelope protein E. (Microbial infection) Interacts with Hepatitis B virus envelope protein. [UniProt] |
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Research Area | Immune System antibody; M1/M2/TAM Marker antibody; Macrophage Marker antibody; M2 Macrophage Marker antibody |
Calculated MW | 166 kDa |
Images (10) Click the Picture to Zoom In
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ARG22372 anti-CD206 / MMR antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Rat colon tissue stained with ARG22372 anti-CD206 / MMR antibody at 5 µg/ml dilution.
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ARG22372 anti-CD206 / MMR antibody WB image
Western blot: 1) Rat brain, 2) Rat kidney, and 3) Mouse brain tissue stained with ARG22372 anti-CD206 / MMR antibody at 1:500 dilution.
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ARG22372 anti-CD206 / MMR antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Rat skin tissue stained with ARG22372 anti-CD206 / MMR antibody at 1:200 dilution.
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ARG22372 anti-CD206 / MMR antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Rat skin tissue stained with ARG22372 anti-CD206 / MMR antibody at 1:100 dilution.
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ARG22372 anti-CD206 / MMR antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Rat kidney tissue stained with ARG22372 anti-CD206 / MMR antibody at 1:100 dilution.
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ARG22372 anti-CD206 / MMR antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Rat brain tissue stained with ARG22372 anti-CD206 / MMR antibody at 1:200 dilution.
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ARG22372 anti-CD206 / MMR antibody IHC-P image
Immunohistochemistry: Formalin-fixed and paraffin-embedded Pig kidney tissue stained with ARG22372 anti-CD206 / MMR antibody at 1:200 dilution.
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ARG22372 anti-CD206 / MMR antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Pig heart tissue stained with ARG22372 anti-CD206 / MMR antibody at 1:200 dilution.
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ARG22372 anti-CD206 / MMR antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Rat kidney tissue stained with ARG22372 anti-CD206 / MMR antibody at 1:200 dilution.
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ARG22372 anti-CD206 / MMR antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Rat brain tissue stained with ARG22372 anti-CD206 / MMR antibody at 1:100 dilution.
Specific References