ARG22184

anti-CD107b / LAMP2 antibody [H4B4] (Biotin)

anti-CD107b / LAMP2 antibody [H4B4] (Biotin) for Electron microscopy,Flow cytometry,ICC/IF,IHC-Frozen sections,IHC-Formalin-fixed paraffin-embedded sections,Purification,Western blot and Human,African green monkey,Rhesus Monkey

Overview

Product Description Biotin-conjugated Mouse Monoclonal antibody [H4B4] recognizes CD107b / LAMP2
Tested Reactivity Hu, AGMK, R. Mk
Tested Application EM, FACS, ICC/IF, IHC-Fr, IHC-P, Puri, WB
Specificity Human/Rhesus/African Green Monkey CD107b
Host Mouse
Clonality Monoclonal
Clone H4B4
Isotype IgG1, kappa
Target Name CD107b / LAMP2
Antigen Species Human
Immunogen Human adherent peripheral blood cells
Conjugation Biotin
Alternate Names CD antigen CD107b; LAMPB; CD107b; LGP110; Lysosome-associated membrane glycoprotein 2; LAMP-2; CD107 antigen-like family member B; Lysosome-associated membrane protein 2

Application Instructions

Application Suggestion
Tested Application Dilution
EMAssay-dependent
FACS10 µl/10^6 cells
ICC/IFAssay-dependent
IHC-FrAssay-dependent
IHC-PAssay-dependent
PuriAssay-dependent
WBAssay-dependent
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Buffer PBS and 0.1% Sodium azide.
Preservative 0.1% Sodium azide
Storage Instruction Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 3920 Human LAMP2

Swiss-port # P13473 Human Lysosome-associated membrane glycoprotein 2

Gene Symbol LAMP2
Gene Full Name lysosomal-associated membrane protein 2
Background The protein encoded by this gene is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. It may play a role in tumor cell metastasis. It may also function in the protection, maintenance, and adhesion of the lysosome. Alternative splicing of this gene results in multiple transcript variants encoding distinct proteins. [provided by RefSeq, Jul 2008]
Function Implicated in tumor cell metastasis. May function in protection of the lysosomal membrane from autodigestion, maintenance of the acidic environment of the lysosome, adhesion when expressed on the cell surface (plasma membrane), and inter- and intracellular signal transduction. Protects cells from the toxic effects of methylating mutagens. [UniProt]
Calculated MW 45 kDa
PTM O- and N-glycosylated; some of the 16 N-linked glycans are polylactosaminoglycans.