ARG56154
anti-Bcl 11B / Ctip2 antibody
anti-Bcl 11B / Ctip2 antibody for Western blot and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes Bcl 11B / Ctip2 |
|---|---|
| Tested Reactivity | Hu |
| Predict Reactivity | Ms |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | Bcl 11B / Ctip2 |
| Antigen Species | Human |
| Immunogen | KLH-conjugated synthetic peptide corresponding to aa. 307-334 (Center) of Human Bcl 11B / Ctip2. |
| Conjugation | Un-conjugated |
| Alternate Names | ZNF856B; ATL1-gamma; COUP-TF-interacting protein 2; ATL1-delta; hRit1; B-cell lymphoma/leukemia 11B; CTIP2; B-cell CLL/lymphoma 11B; CTIP-2; RIT1; ATL1-beta; ATL1; hRIT1-alpha; BCL-11B; Radiation-induced tumor suppressor gene 1 protein; ATL1-alpha |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| Positive Control | Jurkat |
Properties
| Form | Liquid |
|---|---|
| Purification | Purification with Protein A and immunogen peptide. |
| Buffer | PBS and 0.09% (W/V) Sodium azide. |
| Preservative | 0.09% (W/V) Sodium azide |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | BCL11B |
| Gene Full Name | B-cell CLL/lymphoma 11B (zinc finger protein) |
| Background | This gene encodes a C2H2-type zinc finger protein and is closely related to BCL11A, a gene whose translocation may be associated with B-cell malignancies. Although the specific function of this gene has not been determined, the encoded protein is known to be a transcriptional repressor, and is regulated by the NURD nucleosome remodeling and histone deacetylase complex. Four alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Aug 2013] |
| Function | Tumor-suppressor protein involved in T-cell lymphomas. May function on the P53-signaling pathway. May be a key regulator of both differentiation and survival during thymocyte development. Repress transcription through direct, TFCOUP2-independent binding to a GC-rich response element (By similarity). [UniProt] |
| Calculated MW | 96 kDa |
| PTM | Sumoylated with SUMO1. |
Images (1) Click the Picture to Zoom In
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ARG56154 anti-Bcl 11B / Ctip2 antibody WB image
Western blot: 20 µg of Jurkat cell lysate stained with ARG56154 anti-Bcl 11B / Ctip2 antibody at 1:16000 dilution.
