ARG44531
anti-ANAPC1 antibody
anti-ANAPC1 antibody for IHC-Formalin-fixed paraffin-embedded sections,ICC/IF,Western blot,Flow cytometry and Human
Ectodermal dysplasia, Hypotrichosis
Overview
| Product Description | Rabbit Polyclonal antibody recognizes ANAPC1 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | FACS, ICC/IF, IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Target Name | ANAPC1 |
| Antigen Species | Human |
| Immunogen | Human ANAPC1 recombinant protein |
| Conjugation | Un-conjugated |
| Alternate Names | ANAPC1; Anaphase Promoting Complex Subunit 1; TSG24; APC1; MCPR; Anaphase-Promoting Complex Subunit 1; Testis-Specific Gene 24 Protein; Mitotic Checkpoint Regulator; Cyclosome Subunit 1 |
Application Instructions
| Application Suggestion |
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| Application Note | The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 4% Trehalose. |
| Preservative | 0.05% Sodium azide |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
Bioinformation
| Database Links |
Swiss-port # Q9H1A4 Human Anaphase-promoting complex subunit 1 |
|---|---|
| Gene Symbol | ANAPC1 |
| Gene Full Name | Anaphase Promoting Complex Subunit 1 |
| Background | This gene encodes a subunit of the anaphase-promoting complex. This complex is an E3 ubiquitin ligase that regulates progression through the metaphase to anaphase portion of the cell cycle by ubiquitinating proteins which targets them for degradation. |
| Function | Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. |
| Research Area | Ectodermal dysplasia, Hypotrichosis |
| Calculated MW | 217 kDa |
| PTM | Phosphoprotein |
Images (4) Click the Picture to Zoom In
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ARG44531 anti-ANAPC1 antibody IHC-P image
Immunohistochemistry: Human placenta stained with ARG44531 anti-ANAPC1 antibody at 2 μg/mL dilution.
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ARG44531 anti-ANAPC1 antibody ICC/IF image
Immunofluorescence: MCF-7 stained with ARG44531 anti-ANAPC1 antibody at 5 μg/mL dilution.
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ARG44531 anti-ANAPC1 antibody WB image
Western blot: HEK293 and K562 stained with ARG44531 anti-ANAPC1 antibody at 0.5 μg/mL dilution.
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ARG44531 anti-ANAPC1 antibody FACS image
Flow Cytometry: A549 stained with ARG44531 anti-ANAPC1 antibody at 1 μg/10^6 cells dilution.
