ARG63765
anti-AGRP / Agouti related protein antibody
anti-AGRP / Agouti related protein antibody for IHC-Frozen sections and Human
Cell Biology and Cellular Response antibody; Metabolism antibody; Neuroscience antibody; Signaling Transduction antibody
Overview
| Product Description | Goat Polyclonal antibody recognizes AGRP / Agouti related protein |
|---|---|
| Tested Reactivity | Hu |
| Predict Reactivity | Dog, Pig |
| Tested Application | IHC-Fr |
| Specificity | This antibody is expected to recognise both reported isoforms (as represented by NP_001129; NP_015531) |
| Host | Goat |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | AGRP / Agouti related protein |
| Antigen Species | Human |
| Immunogen | CRKLGTAMNPCSRT |
| Conjugation | Un-conjugated |
| Alternate Names | Agouti-related protein; AGRT; ART; ASIP2 |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0) at 80°C for 30 min. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Buffer | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 0.5% BSA |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
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| Background | This gene encodes an antagonist of the melanocortin-3 and melanocortin-4 receptor. It appears to regulate hypothalamic control of feeding behavior via melanocortin receptor and/or intracellular calcium regulation, and thus plays a role in weight homeostasis. Mutations in this gene have been associated with late on-set obesity. [provided by RefSeq, Dec 2009] |
| Research Area | Cell Biology and Cellular Response antibody; Metabolism antibody; Neuroscience antibody; Signaling Transduction antibody |
| Calculated MW | 14 kDa |
Images (1) Click the Picture to Zoom In
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ARG63765 anti-AGRP / Agouti related protein antibody IHC-Fr image
Immunohistochemistry: PFA-perfused cryosection of Human hypothalamus tissue stained with ARG63765 anti-AGRP / Agouti related protein antibody at 0.05 µg/ml dilution.
