ARG30332

NLRC4 Inflammasome Antibody Panel

publication_link Publication16

Component

Cat No Component Name Host clonality Reactivity Application Package
ARG59418 anti-NLRC4 / CARD12 antibody Rabbit pAb Hu, Ms ICC/IF, IHC-P, WB 20 μl
ARG66211 anti-ASC / TMS1 antibody Rabbit pAb Hu, Ms WB 20 μl
ARG57293 anti-Caspase 1 antibody Rabbit pAb Hu, Ms ICC/IF, IHC-P, IP, WB 20 μl
ARG10112 anti-GAPDH antibody [6C5] Mouse mAb Hu, Ms, Rat, AGMK, Bb, Cat, Chk, Dog, Fsh, Hm, Mk, Pig, Rb, Xenopus laevis, Zfsh ELISA, ICC/IF, IHC-Fr, WB 20 μg

Overview

Product Description NLRC4 Inflammasome Antibody Panel is an all-in-one solution to make the research of NLRC4 inflammasome easy and economic. This antibody panel comprises antibodies against the key components of NLRC4 inflammasome including NLRC4, ASC, and Caspase-1. Moreover, a loading control antibody against GAPDH is also included. This panel is the best solution for studying NLRC4 Inflammasome.
Target Name NLRC4 Inflammasome
Alternate Names NLRC4 Inflammasome antibody; GAPDH antibody; Caspase 1 antibody; NLRC4 / CARD12 antibody; ASC / TMS1 antibody

Properties

Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Gene Full Name Antibody Panel for NLRC4 Inflammasome
Highlight Related news:
Inflammasome & Pyroptosis Antibody Panels are released
Exploring Antiviral Immune Response
AMPK signaling regulates NLRP3 inflammation and pyroptosis

Images (19) Click the Picture to Zoom In

  • ARG10112 anti-GAPDH antibody [6C5] WB image

    Western blot: 1) U87-MG 2) HepG2 3) rat brain 4) rat heart 5) rat ovary stained with ARG10112 anti-GAPDH antibody [6C5] at 1:2000 dilution.

  • ARG10112 anti-GAPDH antibody [6C5] ICC/IF image

    Immunofluorescence: 100% Methanol fixed (RT, 10 min) HeLa cells stained with ARG10112 anti-GAPDH antibody [6C5] (green) at 1:200 dilution.

    Secondary antibody: ARG55393 Goat anti-Mouse IgG (H+L) antibody (FITC)

  • ARG57293 anti-Caspase 1 antibody WB image

    Western blot: 10 µg of HeLa and 20 µg of Mouse brain lysates stained with ARG57293 anti-Caspase 1 antibody at 1:1000 dilution.

  • ARG57293 anti-Caspase 1 antibody WB image

    Western blot: 25 µg of cell lysate from PMA treated THP-1 cells were stained with ARG57293 anti-Caspase 1 antibody at 1:1000 dilution.

  • ARG57293 anti-Caspase 1 antibody ICC/IF image

    Immunofluorescence: Raw264.7 cells stained with ARG57293 anti-Caspase 1 antibody at 1:100 dilution.

  • ARG59418 anti-NLRC4 / CARD12 antibody ICC/IF image

    Immunofluorescence: THP-1 cells stained with ARG59418 anti-NLRC4 / CARD12 antibody (red).

  • ARG57293 anti-Caspase 1 antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Mouse kidney tissue stained with ARG57293 anti-Caspase 1 antibody at 1:100 dilution.

  • ARG59418 anti-NLRC4 / CARD12 antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Human lung stained with ARG59418 anti-NLRC4 / CARD12 antibody at 1:100 dilution (40x lens).

  • ARG66211 anti-ASC / TMS1 antibody WB image

    Western blot: 40 µg of HL60, A549, Raji and RAW264.7 cell lysates stained with ARG66211 anti-ASC / TMS1 antibody at 1:500 dilution.

  • ARG59418 anti-NLRC4 / CARD12 antibody WB image

    Western blot: 25 µg of Mouse spleen and U87 cell lysate stained with ARG59418 anti-NLRC4 / CARD12 antibody at 1:3000 dilution.

  • ARG57293 anti-Caspase 1 antibody IP image

    Immunoprecipitation: 200 µg extracts of THP-1 cells Immunoprecipitated and stained with ARG57293 anti-Caspase 1 antibody at 1:1000 dilution.

  • ARG10112 anti-GAPDH antibody [6C5] WB image

    Western blot: 1) U87-MG 2) MCF-7 3) A549 4) DU145 5) SW480 6) rat brain 7) rat stomach 8) rat ovary stained with ARG10112 anti-GAPDH antibody [6C5] at 1:5000 dilution.

  • ARG10112 anti-GAPDH antibody [6C5] WB image

    Western blot: Mouse samples stained with ARG10112 anti-GAPDH antibody [6C5] at 1:1000 dilution.

    From Yun-Yun Li et al. Int J Biol Sci (2022), doi: 10.7150/ijbs.68224, Fig. 5. C.

  • ARG10112 anti-GAPDH antibody [6C5] WB image

    Western blot: Porcine kidney stained with ARG10112 anti-GAPDH antibody [6C5].

    From Jianni Huang et al. Front Cell Dev Biol (2022), doi: 10.3389/fcell.2022.899869, Fig. 2. E.

  • ARG59418 anti-NLRC4 / CARD12 antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Human colon stained with ARG59418 anti-NLRC4 / CARD12 antibody at 1:100 dilution (40x lens).

  • ARG10112 anti-GAPDH antibody [6C5] WB image

    Western blot: pAFs, AcoSV40, and AcoSI-1 stained with ARG10112 anti-GAPDH antibody [6C5] at 1:5000 dilution.

    From Michele N Dill et al. PLoS One. (2023), doi: 10.3389/fcell.2022.899869, Fig. 2. C.

  • ARG59418 anti-NLRC4 / CARD12 antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Human gastric stained with ARG59418 anti-NLRC4 / CARD12 antibody at 1:100 dilution (40x lens).

  • ARG59418 anti-NLRC4 / CARD12 antibody IHC-P image

    Immunohistochemistry: Mouse lung stained with ARG59418 anti-NLRC4 / CARD12 antibody (orange-red).

  • ARG10112 anti-GAPDH antibody [6C5] WB image

    Western blot: 1) MCF-7 2) DU-145 3) A549 4) H1299 5) HCT116 6) HepG2 7) HUVEC stained with ARG10112 anti-GAPDH antibody [6C5] at 1:1000 dilution.

Specific References

PCSK6 exacerbates Alzheimer's disease pathogenesis by promoting MT5-MMP maturation

ARG10112: WB / Human, Mouse

Mingliang Xu et al.
Exp Neurol.,  (2024)

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Biochanin A inhibits cardiac hypertrophy and fibrosis in vivo and in vitro

ARG10112: WB / Mouse, Rat

Zhenyu Feng et al.
Biomed Pharmacother.,  (2024)

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Shionone relieves oxygen-glucose deprivation/reoxygenation induced SH-SY5Y cells injury by inhibiting the p38 MAPK/NF-κB pathway

ARG10112: WB / Human

Xiaoli Zhou et al.
J Cardiothorac Surg,  (2024)

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7,8-Dihydroxyflavone ameliorates cognitive impairment induced by repeated neonatal sevoflurane exposures in mice through increasing tau O-GlcNAcylation

ARG10112: WB / Mouse

Mingliang Xu et al.
Neurosci Lett.,  (2024)

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The effect of long-term administration of green tea catechins on aging-related cardiac diastolic dysfunction and decline of troponin I

ARG10112: WB / Mouse

Junjun Quan et al.
pre-print,  (2024)

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PPARγ activation suppresses chondrocyte ferroptosis through mitophagy in osteoarthritis

ARG10112: WB / Rat

Xiang Xue et al.
J Orthop Surg Res.,  (2023)

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Discovery of the First Subnanomolar PPARα/δ Dual Agonist for the Treatment of Cholestatic Liver Diseases

ARG10112: WB / Mouse

Zhiqi Feng et al.
J Med Chem.,  (2023)

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Knockdown of Porf-2 restores visual function after optic nerve crush injury

ARG10112: WB / Mouse

Di Chen et al.
Cell Death Dis.,  (2023)

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Resveratrol inhibits Toxoplasma gondii-induced lung injury, inflammatory cascade and evidences of its mechanism of action

ARG10112: WB / Mouse

Yu Nan Lu et al.
Phytomedicine.,  (2023)

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Discrepant Activation Pattern of Inflammation and Pyroptosis Induced in Dermal Fibroblasts in Response to Dengue Virus Serotypes 1 and 2 and Nonstructural Protein 1

ARG57293: WB / Human

Kai-Che Wei et al.
Microbiol Spectr.,  (2023)

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Ursolic acid induces apoptosis and pyroptosis in Reh cells by upregulating of the JNK signalling pathway based on network pharmacology and experimental validation

ARG57293: WB / Human

Ying Luo et al.
Heliyon.,  (2023)

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Uric acid mitigates cognitive deficits via transcription factor EB - mediated microglial autophagy in mice models of Alzheimer's disease

ARG10112: WB / Mouse

Qian Xiao et al.
,  (2023)

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黄芪甲苷预处理对大鼠肠缺血再灌注所致肺损伤的影响及其机制

ARG10112, ARG57293, ARG66211: WB / Rat

王蕾 et al.
中国中西医结合外科杂志,  (2023)

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Curcumin improves the function of umbilical vein endothelial cells by inhibiting H2O2‑induced pyroptosis

ARG57293:IF, WB / Human

Yulin Yuan et al.
Mol Med Rep,  (2022)

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Curcumin improves the function of umbilical vein endothelial cells by inhibiting H2O2 induced pyroptosis

ARG57293:IF / Human

Yulin Yuan et al.
Molecular Medicine Reports,  (2022)

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Protective effect of ginsenoside Rh2 against Toxoplasma gondii infection-induced neuronal injury through binding TgCDPK1 and NLRP3 to inhibit microglial NLRP3 inflammasome signaling pathway

ARG57293: WB / Mouse

Guang-Nan Jin et al.
Int Immunopharmacol.,  (2022)

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